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• W3110194416 startingPage "2000052" @default.
• W3110194416 abstract "Metabolomics, including lipidomics, is emerging as a quantitative biology approach for the assessment of energy flow through metabolism and information flow through metabolic signaling; thus, providing novel insights into metabolism and its regulation, in health, healthy ageing and disease. In this forward-looking review we provide an overview on the origins of metabolomics, on its role in this postgenomic era of biochemistry and its application to investigate metabolite role and (bio)activity, from model systems to human population studies. We present the challenges inherent to this analytical science, and approaches and modes of analysis that are used to resolve, characterize and measure the infinite chemical diversity contained in the metabolome (including lipidome) of complex biological matrices. In the current outbreak of metabolic diseases such as cardiometabolic disorders, cancer and neurodegenerative diseases, metabolomics appears to be ideally situated for the investigation of disease pathophysiology from a metabolite perspective." @default.
• W3110194416 created "2020-12-07" @default.
• W3110194416 creator A5077405324 @default.
• W3110194416 creator A5083697454 @default.
• W3110194416 creator A5089048513 @default.
• W3110194416 date "2020-11-24" @default.
• W3110194416 modified "2023-10-17" @default.
• W3110194416 title "Metabolomics meets lipidomics: Assessing the small molecule component of metabolism" @default.
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