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- W3110235021 endingPage "5851" @default.
- W3110235021 startingPage "5844" @default.
- W3110235021 abstract "In the last decades, more efforts are focused on the prevention and treatment of malignant diseases, given the increase in all cancers incidence A lifestyle change, including healthy eating habits and regular physical activity, has significantly impacted colorectal cancer prevention. The effect of dose-dependent physical activity on mortality and recurrence rates of colorectal carcinoma has been unequivocally demonstrated in observational studies. However, clear recommendations are not available on the frequency, duration, and intensity of exercise in patients with colorectal cancer due to the lack of evidence in randomized clinical trials. Regarding pathophysiological mechanisms, the most plausible explanation appears to be the influence of physical activity on reducing chronic inflammation and insulin resistance with a consequent positive effect on insulin growth factor 1 signaling pathways." @default.
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- W3110235021 date "2020-12-06" @default.
- W3110235021 modified "2023-10-18" @default.
- W3110235021 title "What is the gut feeling telling us about physical activity in colorectal carcinogenesis?" @default.
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- W3110235021 doi "https://doi.org/10.12998/wjcc.v8.i23.5844" @default.
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