Matches in SemOpenAlex for { <https://semopenalex.org/work/W3110278418> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3110278418 abstract "Herewith, we review an updated progress of regenerative medical products using human embryonic stem cells (ESCs) in Japan. Two groups from Kyoto University and the National Center for Child Health and Development (NCCHD) established a novel derivation/cultivation system of ESCs for potential application in translational and clinical research. At the first stage of ESC derivation, murine feeder cells have been used in line with Japanese guidelines on public health associated with the implementation of the xenograft. To avoid exposure of ESCs to animal products in culture media, a xeno-free cultivating system has been established. Twelve ESCs (KhES-1, KhES-2, KhES-3, KhES-4, KhES-5, SEES-1, SEES-2, SEES-3, SEES-4, SEES-5, SEES-6, and SEES-7) are now available under a clinically relevant platform for industrially and clinically applicable regenerative medical products. NCCHD submitted an investigative new drug application to the Pharmaceuticals and Medical Devices Agency (PMDA) for using ESC-based products in patients with hyperammonemia due to genetic defects on March 2018 under the Pharmaceutical Affairs Law (now revised to the Pharmaceuticals, Medical Devices, and Other Therapeutic Products Act). Currently, up to ten ESC-based products are being prepared for intractable and rare disorders in Japan." @default.
- W3110278418 created "2020-12-07" @default.
- W3110278418 creator A5003185407 @default.
- W3110278418 creator A5016298609 @default.
- W3110278418 creator A5027421629 @default.
- W3110278418 creator A5038402214 @default.
- W3110278418 creator A5056307493 @default.
- W3110278418 creator A5056517213 @default.
- W3110278418 creator A5060983001 @default.
- W3110278418 creator A5061331494 @default.
- W3110278418 creator A5091477080 @default.
- W3110278418 date "2020-01-01" @default.
- W3110278418 modified "2023-09-24" @default.
- W3110278418 title "Research and Development Strategy for Future Embryonic Stem Cell-Based Therapy in Japan" @default.
- W3110278418 cites W1600024584 @default.
- W3110278418 cites W1667282266 @default.
- W3110278418 cites W2024334977 @default.
- W3110278418 cites W2068437492 @default.
- W3110278418 cites W2197714088 @default.
- W3110278418 cites W2206030442 @default.
- W3110278418 cites W2219174566 @default.
- W3110278418 cites W2278743348 @default.
- W3110278418 cites W2291481466 @default.
- W3110278418 cites W2495130116 @default.
- W3110278418 cites W2558570141 @default.
- W3110278418 cites W2575557755 @default.
- W3110278418 cites W2757032260 @default.
- W3110278418 cites W2772717429 @default.
- W3110278418 cites W2790484925 @default.
- W3110278418 cites W2884305074 @default.
- W3110278418 cites W2951031454 @default.
- W3110278418 doi "https://doi.org/10.31662/jmaj.2018-0029" @default.
- W3110278418 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7676987" @default.
- W3110278418 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33225099" @default.
- W3110278418 hasPublicationYear "2020" @default.
- W3110278418 type Work @default.
- W3110278418 sameAs 3110278418 @default.
- W3110278418 citedByCount "5" @default.
- W3110278418 countsByYear W31102784182021 @default.
- W3110278418 countsByYear W31102784182022 @default.
- W3110278418 crossrefType "journal-article" @default.
- W3110278418 hasAuthorship W3110278418A5003185407 @default.
- W3110278418 hasAuthorship W3110278418A5016298609 @default.
- W3110278418 hasAuthorship W3110278418A5027421629 @default.
- W3110278418 hasAuthorship W3110278418A5038402214 @default.
- W3110278418 hasAuthorship W3110278418A5056307493 @default.
- W3110278418 hasAuthorship W3110278418A5056517213 @default.
- W3110278418 hasAuthorship W3110278418A5060983001 @default.
- W3110278418 hasAuthorship W3110278418A5061331494 @default.
- W3110278418 hasAuthorship W3110278418A5091477080 @default.
- W3110278418 hasBestOaLocation W31102784181 @default.
- W3110278418 hasConcept C104317684 @default.
- W3110278418 hasConcept C108170787 @default.
- W3110278418 hasConcept C10854531 @default.
- W3110278418 hasConcept C127413603 @default.
- W3110278418 hasConcept C144024400 @default.
- W3110278418 hasConcept C145103041 @default.
- W3110278418 hasConcept C150903083 @default.
- W3110278418 hasConcept C28328180 @default.
- W3110278418 hasConcept C36289849 @default.
- W3110278418 hasConcept C54355233 @default.
- W3110278418 hasConcept C55587333 @default.
- W3110278418 hasConcept C71924100 @default.
- W3110278418 hasConcept C86803240 @default.
- W3110278418 hasConcept C95444343 @default.
- W3110278418 hasConceptScore W3110278418C104317684 @default.
- W3110278418 hasConceptScore W3110278418C108170787 @default.
- W3110278418 hasConceptScore W3110278418C10854531 @default.
- W3110278418 hasConceptScore W3110278418C127413603 @default.
- W3110278418 hasConceptScore W3110278418C144024400 @default.
- W3110278418 hasConceptScore W3110278418C145103041 @default.
- W3110278418 hasConceptScore W3110278418C150903083 @default.
- W3110278418 hasConceptScore W3110278418C28328180 @default.
- W3110278418 hasConceptScore W3110278418C36289849 @default.
- W3110278418 hasConceptScore W3110278418C54355233 @default.
- W3110278418 hasConceptScore W3110278418C55587333 @default.
- W3110278418 hasConceptScore W3110278418C71924100 @default.
- W3110278418 hasConceptScore W3110278418C86803240 @default.
- W3110278418 hasConceptScore W3110278418C95444343 @default.
- W3110278418 hasIssue "4" @default.
- W3110278418 hasLocation W31102784181 @default.
- W3110278418 hasLocation W31102784182 @default.
- W3110278418 hasLocation W31102784183 @default.
- W3110278418 hasOpenAccess W3110278418 @default.
- W3110278418 hasPrimaryLocation W31102784181 @default.
- W3110278418 hasRelatedWork W1973981707 @default.
- W3110278418 hasRelatedWork W1979047014 @default.
- W3110278418 hasRelatedWork W2036241096 @default.
- W3110278418 hasRelatedWork W2048656432 @default.
- W3110278418 hasRelatedWork W2065653704 @default.
- W3110278418 hasRelatedWork W2091271152 @default.
- W3110278418 hasRelatedWork W2135700299 @default.
- W3110278418 hasRelatedWork W2236280261 @default.
- W3110278418 hasRelatedWork W2377856504 @default.
- W3110278418 hasRelatedWork W4285255068 @default.
- W3110278418 hasVolume "3" @default.
- W3110278418 isParatext "false" @default.
- W3110278418 isRetracted "false" @default.
- W3110278418 magId "3110278418" @default.
- W3110278418 workType "article" @default.