Matches in SemOpenAlex for { <https://semopenalex.org/work/W3110362609> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W3110362609 abstract "Abstract Background It has been suggested that maternal cardiac adaptations during pregnancy differ between nulliparous and multipara women and also vary according to the age. Impaired cardiac function precedes pre-eclampsia. Purpose To evaluate effect of age and parity on maternal cardiac diastolic function in middle trimester among pregnant women with normal left ventricular ejection fraction as well as correlation between impaired diastolic function and pre-eclampsia. Methods Pregnant women with singleton pregnancies carried from 13 weeks to 20 weeks and left ventricular ejection fraction (LVEF) ≥50% were identified. Diastolic function parameters were assessed using transthoracic echocardiography. Pre-eclampsia was identified from medical records. Results 376 pregnant women were included (median age: 30 years; median gestational age: 14 weeks; 171 multiparous women). LVEF was 66%. Impaired cardiac diastolic function was seen in 7.8% of pregnant women <35 years compared with 28.6% of those ≥35 years (p=0.000). ROC curve showed women with maternal age over 32 began to have a higher rate of impaired cardiac diastolic function (AUC=0.704, p=0.000, sensitivity=54.5%, specificity=75.3%). There was no difference in diastolic function indices between maternal women grouped by parity. After adjustment for confounders, maternal age can be independent effect factor of Em declined (P<0.05). Em<13cm/s was significantly associated with pre-eclampsia occurrence (HR 8.56; 95% CI: 3.40–21.57) after adjusting for the confounders. Conclusion Maternal age is an independent impact factor for diastolic function decline. There is no difference in cardiac diastolic function between nullipara and multipara. Pre-eclampsia occurrence is significantly higher in patients with diastolic function decline at mid-gestation. The utility of risk stratification using diastolic function at mid-gestation may improve the survival outcomes of pregnant women. Association between Em and PE risk Funding Acknowledgement Type of funding source: None" @default.
- W3110362609 created "2020-12-07" @default.
- W3110362609 creator A5018781720 @default.
- W3110362609 creator A5029873947 @default.
- W3110362609 creator A5031753981 @default.
- W3110362609 creator A5079542540 @default.
- W3110362609 date "2020-11-01" @default.
- W3110362609 modified "2023-09-23" @default.
- W3110362609 title "Effect of age and parity on maternal diastolic function in middle trimester pregnant women with normal left ventricular ejection fraction and potential link of diastolic function to pre-eclampsia" @default.
- W3110362609 doi "https://doi.org/10.1093/ehjci/ehaa946.0038" @default.
- W3110362609 hasPublicationYear "2020" @default.
- W3110362609 type Work @default.
- W3110362609 sameAs 3110362609 @default.
- W3110362609 citedByCount "0" @default.
- W3110362609 crossrefType "journal-article" @default.
- W3110362609 hasAuthorship W3110362609A5018781720 @default.
- W3110362609 hasAuthorship W3110362609A5029873947 @default.
- W3110362609 hasAuthorship W3110362609A5031753981 @default.
- W3110362609 hasAuthorship W3110362609A5079542540 @default.
- W3110362609 hasConcept C111566952 @default.
- W3110362609 hasConcept C126322002 @default.
- W3110362609 hasConcept C131872663 @default.
- W3110362609 hasConcept C164705383 @default.
- W3110362609 hasConcept C2778198053 @default.
- W3110362609 hasConcept C2778376644 @default.
- W3110362609 hasConcept C2779234561 @default.
- W3110362609 hasConcept C2781276381 @default.
- W3110362609 hasConcept C54355233 @default.
- W3110362609 hasConcept C57900726 @default.
- W3110362609 hasConcept C71924100 @default.
- W3110362609 hasConcept C77350462 @default.
- W3110362609 hasConcept C78085059 @default.
- W3110362609 hasConcept C84393581 @default.
- W3110362609 hasConcept C86803240 @default.
- W3110362609 hasConceptScore W3110362609C111566952 @default.
- W3110362609 hasConceptScore W3110362609C126322002 @default.
- W3110362609 hasConceptScore W3110362609C131872663 @default.
- W3110362609 hasConceptScore W3110362609C164705383 @default.
- W3110362609 hasConceptScore W3110362609C2778198053 @default.
- W3110362609 hasConceptScore W3110362609C2778376644 @default.
- W3110362609 hasConceptScore W3110362609C2779234561 @default.
- W3110362609 hasConceptScore W3110362609C2781276381 @default.
- W3110362609 hasConceptScore W3110362609C54355233 @default.
- W3110362609 hasConceptScore W3110362609C57900726 @default.
- W3110362609 hasConceptScore W3110362609C71924100 @default.
- W3110362609 hasConceptScore W3110362609C77350462 @default.
- W3110362609 hasConceptScore W3110362609C78085059 @default.
- W3110362609 hasConceptScore W3110362609C84393581 @default.
- W3110362609 hasConceptScore W3110362609C86803240 @default.
- W3110362609 hasLocation W31103626091 @default.
- W3110362609 hasOpenAccess W3110362609 @default.
- W3110362609 hasPrimaryLocation W31103626091 @default.
- W3110362609 hasRelatedWork W1765992 @default.
- W3110362609 hasRelatedWork W18785417 @default.
- W3110362609 hasRelatedWork W4481142 @default.
- W3110362609 hasRelatedWork W9070863 @default.
- W3110362609 hasRelatedWork W9482636 @default.
- W3110362609 hasRelatedWork W9714178 @default.
- W3110362609 hasRelatedWork W10958683 @default.
- W3110362609 hasRelatedWork W18066817 @default.
- W3110362609 hasRelatedWork W3250691 @default.
- W3110362609 hasRelatedWork W7675600 @default.
- W3110362609 isParatext "false" @default.
- W3110362609 isRetracted "false" @default.
- W3110362609 magId "3110362609" @default.
- W3110362609 workType "article" @default.