Matches in SemOpenAlex for { <https://semopenalex.org/work/W3110367164> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W3110367164 abstract "Abstract Background : Uterine clear cell carcinoma (UCCC) is a rare histological type of endometrial cancer with poor prognosis and high risk of tumor relapse. Although adjuvant chemotherapy (CT) and/or radiotherapy (RT) are often recommended for early stage UCCC patients, the effectiveness of these treatment strategies remains unclear. Methods : Systematic review and meta-analysis were applied to evaluate treatment-related outcomes of stage I-II UCCC patients. Search strategy was applied using electronic databases until June 1st, 2019. Inclusion criteria were retrospective, observational and prospective studies that reported outcome of UCCC patients receiving adjuvant therapy. Clinical endpoints like overall survival (OS) and progression-free survival (PFS) were evaluated. Data were extracted by two independent reviewers and a meta-analysis was performed. Results : 12 articles with a total of 3845 patients were analyzed. Overall, adjuvant CT after surgery could improve 5 year-OS significantly compared to patients without CT (odds ratio (OR): 0.75, 95% confidence interval (CI): 0.58-0.95; p=0.02). In comparison, RT could also improve OS in UCCC patients of early stage (OR: 0.61, 95% CI: 0.46-0.82; p=0.001) compared to the patients without RT, in US and Europe patients. Lastly, when comparing the patients undergoing both CT and RT with those receiving CT or RT alone, no further improvement in OS was observed (OR: 0.95, 95% CI: 0.53-1.72; P=0.88). Conclusions : Either CT or RT after surgery could improve the OS of early stage of UCCC patients. However, combinatorial CT and RT treatment did not improve the OS compared with CT or RT treatment alone." @default.
- W3110367164 created "2020-12-07" @default.
- W3110367164 creator A5005031025 @default.
- W3110367164 creator A5005838535 @default.
- W3110367164 creator A5007910885 @default.
- W3110367164 creator A5034304769 @default.
- W3110367164 creator A5044544424 @default.
- W3110367164 creator A5058368547 @default.
- W3110367164 creator A5073772432 @default.
- W3110367164 creator A5085218636 @default.
- W3110367164 date "2020-09-09" @default.
- W3110367164 modified "2023-10-17" @default.
- W3110367164 title "Outcomes in patients with early stage uterine clear cell carcinoma treated with chemotherapy and radiotherapy: A systematic review and meta-analysis" @default.
- W3110367164 cites W1994720359 @default.
- W3110367164 cites W2019777872 @default.
- W3110367164 cites W2037845737 @default.
- W3110367164 cites W2061365028 @default.
- W3110367164 cites W2065949107 @default.
- W3110367164 cites W2092789117 @default.
- W3110367164 cites W2115516019 @default.
- W3110367164 cites W2156134814 @default.
- W3110367164 cites W2161558604 @default.
- W3110367164 cites W2163600417 @default.
- W3110367164 cites W2183761249 @default.
- W3110367164 cites W2467784537 @default.
- W3110367164 cites W2468311487 @default.
- W3110367164 cites W2475278217 @default.
- W3110367164 cites W2767070097 @default.
- W3110367164 cites W2787725515 @default.
- W3110367164 cites W2791829934 @default.
- W3110367164 cites W2889144820 @default.
- W3110367164 cites W76374557 @default.
- W3110367164 doi "https://doi.org/10.21203/rs.2.20417/v3" @default.
- W3110367164 hasPublicationYear "2020" @default.
- W3110367164 type Work @default.
- W3110367164 sameAs 3110367164 @default.
- W3110367164 citedByCount "0" @default.
- W3110367164 crossrefType "posted-content" @default.
- W3110367164 hasAuthorship W3110367164A5005031025 @default.
- W3110367164 hasAuthorship W3110367164A5005838535 @default.
- W3110367164 hasAuthorship W3110367164A5007910885 @default.
- W3110367164 hasAuthorship W3110367164A5034304769 @default.
- W3110367164 hasAuthorship W3110367164A5044544424 @default.
- W3110367164 hasAuthorship W3110367164A5058368547 @default.
- W3110367164 hasAuthorship W3110367164A5073772432 @default.
- W3110367164 hasAuthorship W3110367164A5085218636 @default.
- W3110367164 hasBestOaLocation W31103671641 @default.
- W3110367164 hasConcept C126322002 @default.
- W3110367164 hasConcept C141071460 @default.
- W3110367164 hasConcept C143998085 @default.
- W3110367164 hasConcept C146357865 @default.
- W3110367164 hasConcept C151730666 @default.
- W3110367164 hasConcept C156957248 @default.
- W3110367164 hasConcept C2776694085 @default.
- W3110367164 hasConcept C2777546739 @default.
- W3110367164 hasConcept C2777863537 @default.
- W3110367164 hasConcept C2777982462 @default.
- W3110367164 hasConcept C44249647 @default.
- W3110367164 hasConcept C509974204 @default.
- W3110367164 hasConcept C71924100 @default.
- W3110367164 hasConcept C86803240 @default.
- W3110367164 hasConcept C95190672 @default.
- W3110367164 hasConceptScore W3110367164C126322002 @default.
- W3110367164 hasConceptScore W3110367164C141071460 @default.
- W3110367164 hasConceptScore W3110367164C143998085 @default.
- W3110367164 hasConceptScore W3110367164C146357865 @default.
- W3110367164 hasConceptScore W3110367164C151730666 @default.
- W3110367164 hasConceptScore W3110367164C156957248 @default.
- W3110367164 hasConceptScore W3110367164C2776694085 @default.
- W3110367164 hasConceptScore W3110367164C2777546739 @default.
- W3110367164 hasConceptScore W3110367164C2777863537 @default.
- W3110367164 hasConceptScore W3110367164C2777982462 @default.
- W3110367164 hasConceptScore W3110367164C44249647 @default.
- W3110367164 hasConceptScore W3110367164C509974204 @default.
- W3110367164 hasConceptScore W3110367164C71924100 @default.
- W3110367164 hasConceptScore W3110367164C86803240 @default.
- W3110367164 hasConceptScore W3110367164C95190672 @default.
- W3110367164 hasLocation W31103671641 @default.
- W3110367164 hasLocation W31103671642 @default.
- W3110367164 hasOpenAccess W3110367164 @default.
- W3110367164 hasPrimaryLocation W31103671641 @default.
- W3110367164 hasRelatedWork W2027893081 @default.
- W3110367164 hasRelatedWork W2047252483 @default.
- W3110367164 hasRelatedWork W2074274808 @default.
- W3110367164 hasRelatedWork W2286371484 @default.
- W3110367164 hasRelatedWork W2318119155 @default.
- W3110367164 hasRelatedWork W2387957804 @default.
- W3110367164 hasRelatedWork W2401392746 @default.
- W3110367164 hasRelatedWork W2747332931 @default.
- W3110367164 hasRelatedWork W2943907239 @default.
- W3110367164 hasRelatedWork W3140477201 @default.
- W3110367164 isParatext "false" @default.
- W3110367164 isRetracted "false" @default.
- W3110367164 magId "3110367164" @default.
- W3110367164 workType "article" @default.