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- W3110368620 abstract "Lithium represents a cornerstone treatment for bipolar disorder (BD), and its putative mechanisms of action represent a potential avenue toward the neurobiological understanding of the illness. The predictive value of varying course specifiers of BD seems suboptimal. Therefore the assessment and integration of biomarkers of various modalities (e.g., neuroimaging, peripheral biomarkers, and proteomic, metabolomic, and genomic biomarkers) have the potential to predict therapeutic response to lithium and also to unravel novel pathophysiological mechanisms of BD. This chapter provides a critical summary of potential biomarkers and biosignatures of lithium response with the ultimate goal of promoting a more patient-tailored approach toward the lithium treatment of BD." @default.
- W3110368620 created "2020-12-07" @default.
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- W3110368620 date "2021-01-01" @default.
- W3110368620 modified "2023-09-23" @default.
- W3110368620 title "Is there a biosignature for lithium response in bipolar disorder? Evidence and implications" @default.
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- W3110368620 doi "https://doi.org/10.1016/b978-0-12-819182-8.00034-x" @default.
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