FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3110550391> ?p ?o ?g. }

• W3110550391 endingPage "2800" @default.
• W3110550391 startingPage "2799" @default.
• W3110550391 abstract "A 75-year-old man with atrial fibrillation taking amiodarone and apixaban, heart failure with an ejection fraction of 20%, and long QT interval presented for evaluation of progressive swelling and erythema of the right fifth finger over 5 months. He had no known trauma to the hand or unusual exposures. He owned a cat and enjoyed the outdoors. On examination, he had a small nodular papule on the right fifth digit with surrounding fusiform swelling and erythema (Figure 1). The left hand was unaffected. He underwent magnetic resonance imaging of the right hand and forearm, which revealed a complex fluid collection in the extensor compartment. Aspiration of the digit was obtained, which revealed approximately 87,000 total nucleated cells with 85% neutrophils, concerning for infectious tenosynovitis. Given the chronicity of his presentation and the lack of acute systemic toxicity, indolent processes (primarily fungal, mycobacterial, or Nocardia spp.) were on the differential. The patient underwent surgical debridement. Operative culture revealed yeast forms with rare cigar bodies, which were eventually identified as Sporothrix schenckii (Figures 2 and 3).Figure 2Cigar bodies in yeast culture, suggestive of Sporothrix spp.View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 3Conidium of Sporothrix shenckii in yeast culture.View Large Image Figure ViewerDownload Hi-res image Download (PPT) Sporotrichosis is an endemic mycosis caused by the eponymous dimorphic fungus. Traditionally, it has been associated with inoculation through small breaks in the skin, garnering the name “rose gardener’s disease.”1Kauffman C.A. Pappas P.G. Sobel J.D. Pappas P.G. Sporotrichosis.in: Kauffman C.A. Pappas P.G. Sobel J.D. Dismukes W.E. Essentials of Clinical Mycology. Springer, New York2011: 387-397Crossref Scopus (18) Google Scholar Culture is the criterion standard for diagnosis, and often several months of treatment with itraconazole2de Lima Barros M.B. Schubach A.O. de Vasconcellos Carvalhaes de Oliveira R. Martins E.B. Teixeira J.L. Wanke B. Treatment of cutaneous sporotrichosis with itraconazole—study of 645 patients.Clin Infect Dis. 2011; 52: e200-e206Crossref PubMed Scopus (99) Google Scholar or terbinafine are required to eradicate the infection. This patient was treated with terbinafine because of interactions with itraconazole and apixaban3Vranckx P. Valgimigli M. Heidbuchel H. The significance of drug-drug and drug-food interactions of oral anticoagulation.Arrhythm Electrophysiol Rev. 2018; 7: 55-61Crossref PubMed Scopus (80) Google Scholar as well as the negative iontropic effects and QT-prolonging properties of itraconazole.4Qu Y. Fang M. Gao B. et al.Itraconazole decreases left ventricular contractility in isolated rabbit heart: mechanism of action.Toxicol Appl Pharmacol. 2013; 268: 113-122Crossref PubMed Scopus (23) Google Scholar We specially thank Amber Milone, BS, for providing the culture photos." @default.
• W3110550391 created "2020-12-07" @default.
• W3110550391 creator A5081951764 @default.
• W3110550391 creator A5090907413 @default.
• W3110550391 date "2020-12-01" @default.
• W3110550391 modified "2023-10-18" @default.
• W3110550391 title "A Red, Swollen Finger" @default.
• W3110550391 cites W2050644529 @default.
• W3110550391 cites W2165051168 @default.
• W3110550391 cites W2923408498 @default.
• W3110550391 doi "https://doi.org/10.1016/j.mayocp.2020.09.024" @default.
• W3110550391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33276847" @default.
• W3110550391 hasPublicationYear "2020" @default.
• W3110550391 type Work @default.
• W3110550391 sameAs 3110550391 @default.
• W3110550391 citedByCount "0" @default.
• W3110550391 crossrefType "journal-article" @default.
• W3110550391 hasAuthorship W3110550391A5081951764 @default.
• W3110550391 hasAuthorship W3110550391A5090907413 @default.
• W3110550391 hasBestOaLocation W31105503911 @default.
• W3110550391 hasConcept C142724271 @default.
• W3110550391 hasConcept C16005928 @default.
• W3110550391 hasConcept C21717790 @default.
• W3110550391 hasConcept C2776872704 @default.
• W3110550391 hasConcept C2777168789 @default.
• W3110550391 hasConcept C2777250718 @default.
• W3110550391 hasConcept C2779121184 @default.
• W3110550391 hasConcept C2779222958 @default.
• W3110550391 hasConcept C2781156865 @default.
• W3110550391 hasConcept C54355233 @default.
• W3110550391 hasConcept C71924100 @default.
• W3110550391 hasConcept C86803240 @default.
• W3110550391 hasConceptScore W3110550391C142724271 @default.
• W3110550391 hasConceptScore W3110550391C16005928 @default.
• W3110550391 hasConceptScore W3110550391C21717790 @default.
• W3110550391 hasConceptScore W3110550391C2776872704 @default.
• W3110550391 hasConceptScore W3110550391C2777168789 @default.
• W3110550391 hasConceptScore W3110550391C2777250718 @default.
• W3110550391 hasConceptScore W3110550391C2779121184 @default.
• W3110550391 hasConceptScore W3110550391C2779222958 @default.
• W3110550391 hasConceptScore W3110550391C2781156865 @default.
• W3110550391 hasConceptScore W3110550391C54355233 @default.
• W3110550391 hasConceptScore W3110550391C71924100 @default.
• W3110550391 hasConceptScore W3110550391C86803240 @default.
• W3110550391 hasIssue "12" @default.
• W3110550391 hasLocation W31105503911 @default.
• W3110550391 hasOpenAccess W3110550391 @default.
• W3110550391 hasPrimaryLocation W31105503911 @default.
• W3110550391 hasRelatedWork W156826468 @default.
• W3110550391 hasRelatedWork W2021400768 @default.
• W3110550391 hasRelatedWork W2024190701 @default.
• W3110550391 hasRelatedWork W2072059099 @default.
• W3110550391 hasRelatedWork W2329846945 @default.
• W3110550391 hasRelatedWork W2441895518 @default.
• W3110550391 hasRelatedWork W2887470891 @default.
• W3110550391 hasRelatedWork W2945659477 @default.
• W3110550391 hasRelatedWork W3104131780 @default.
• W3110550391 hasRelatedWork W4226071760 @default.
• W3110550391 hasVolume "95" @default.
• W3110550391 isParatext "false" @default.
• W3110550391 isRetracted "false" @default.
• W3110550391 magId "3110550391" @default.
• W3110550391 workType "article" @default.