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- W3110617323 abstract "The clinical outcome of six skin melanoma BNCT irradiations is presented. Three patients (A, B and C), with multiple subcutaneous skin metastases progressed to chemotherapy were infused with {approx}14 g/m{sup 2} of boronophenylalanine ({sup 10}BPA)-fructose and irradiated in the hyperthermal neutron beam of the RA-6 reactor. Patient A received two one fraction irradiations in different areas of the leg, B received one fraction and C was irradiated in three consecutive fields at the calf, heel and foot sole. The maximum prescribed dose to normal skin ranged from 16.5 to 24 Gy-Eq. With a minimum follow-up of 10 months there was a G1 acute epithelitis in A and B and a G3 in C. No late toxicity was observed. Due to the in-field tumor-growth-delay and the absence of severe acute and/or late toxicity observed during the follow-up period, a dose-escalation trial is ongoing. (author)" @default.
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- W3110617323 date "2006-07-01" @default.
- W3110617323 modified "2023-09-27" @default.
- W3110617323 title "BNCT clinical trials of skin melanoma patients in Argentina" @default.
- W3110617323 hasPublicationYear "2006" @default.
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