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- W3110714456 abstract "Background: Vitamin D3 can adjust glycemic control and spot to their etiological factor on type 1 diabetes (T1D), increased transcription of insulin receptor genes by 1, 25 (OH) D. types 1 diabetes is associated with magnesium deficiency. Antibody against Zn-transport 8 has been well documented as a diagnostic consideration for T1D Objective: Evaluate efficacy of Vitamin D3 plus magnesium and zinc for tight glycemic control and decrement in symptoms and sign of type 1 diabetes (T1D) and/or diabetic ketoacidosis in pediatric age group. Patients and Methods: double‐blind placebo‐controlled Fifty patient type 1 diabetes (T1D) child under 16 years from outpatient clinic of pediatrics department in Tikrit teaching and /or salahaldeen teaching Hospital were collected and admitted as inpatient from 2 January 2012 to 2 June 2019. 25 Child ((vitamin D3 magnesium, zinc)) group were take regime as (800 IU/day of vitamin D3, Magnesium 3 mg/kg/d and zinc 2 mg per day) for 180 day, oral capsule prior to meal once daily. 25 Child were received (placebo capsule) as control group for 180 days. Both groups receive recommended dose of insulin twice daily. Results : The Decrement in rate, mean ± SD of symptoms and sign of type 1 diabetes (T1D) at 4 month of ((vitamin D3 magnesium, zinc)) group for Polydipsia11 9.5 (1.4), Glycosuria10 9.2(1.1), Hyperglycemia 108.2 (1.8), were significantly less than rate, mean ± SD of symptoms and sign of type 1 diabetes (T1D) at 4 month of Placebo group for Polydipsia23 20.0(2.5),Glycosuria 2119.52(1.48), Hyperglycemia 24 20.74 (3.26). The Decrement in rate, mean ± SD of Symptoms and sign of diabetic ketoacidosis at 4 month of ((vitamin D3 magnesium, zinc)) group for Acidotic breathing11 10.9(1.3),blood sugar" @default.
- W3110714456 created "2020-12-21" @default.
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- W3110714456 date "2020-01-01" @default.
- W3110714456 modified "2023-09-27" @default.
- W3110714456 title "Double-Blind Placebo‐Controlled Effectiveness of Cholecalciferol (Vitamin D3) Plus Magnesium and Zinc in Management of Type 1 Diabetes (T1d) In Pediatric Age Group -" @default.
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