FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3110714937> ?p ?o ?g. }

• W3110714937 endingPage "110598" @default.
• W3110714937 startingPage "110598" @default.
• W3110714937 abstract "The menopausal transition is a hormonally sensitive period associated with changes in body weight. Phthalates are ubiquitous endocrine disrupting chemicals that could disrupt weight homeostasis, but it is unknown whether this occurs during the menopausal transition.Our objectives were to (1) determine if phthalate exposure in pre- and perimenopausal women was associated with one-year change in body mass index (BMI), and (2) determine if these associations differed across the menopausal transition.We addressed our objectives using data from 524 participants enrolled in the Midlife Women's Health Study. We calculated change in BMI from baseline to first follow-up visit approximately one year later. Phthalate exposures were approximated by measuring urinary metabolites in pools of two-to-four spot urine samples collected across a four-week period at baseline. We molar-converted and summed mono-(2-ethylhexyl) phthalate (mEHP), mono (2-ethyl-5-hydroxyhexyl) phthalate (mEHHP), mono (2-ethyl-5-oxohexyl) phthalate (mEOHP), and mono (2-ethyl-5-carboxypentyl) phthalate (mECPP) to approximate exposure to di-(2-ethylhexyl) phthalate (∑DEHP); ∑DEHP, mono (3-carboxypropyl) phthalate (mCPP), and monobenzyl phthalate (mBzP) to approximate exposure to plasticizer phthalates (∑Plastics); and monoethyl phthalate (mEP), monobutyl phthalate (mBP), and monoisobutyl phthalate (miBP) to approximate exposure to phthalates from personal care products (∑PCP). We used multivariable linear regression models to evaluate associations of specific gravity-adjusted ln-transformed phthalate metabolites or sums with one-year BMI change, and also considered whether associations differed depending on each woman's menopausal status change from baseline to first follow-up.At baseline, most women were premenopausal (67.8%), non-Hispanic white (67.9%), and college educated (65.8%). Overall, urinary phthalate metabolites or sums were not associated with one-year BMI change. Stratified analysis identified positive associations between ∑DEHP (and three of its metabolites: MEHP, MEHHP, and MEOHP) and one-year BMI change among women who transitioned from peri-to post-menopause from baseline to first follow-up. For example, in these women, with each doubling of ∑DEHP, BMI increased by 0.65 kg/m2 (95%CI: 0.17, 1.13) from baseline to first follow-up. Personal care product-associated phthalate metabolites (mBP and mEP) were negatively associated with one-year BMI change among women who remained perimenopausal from baseline to first follow-up, while miBP and mEP were positively associated with one-year BMI change among women who transitioned from peri-to post-menopause.We found the strongest associations between some phthalates and one-year BMI change in women who transitioned from peri-to post-menopause from baseline to first follow-up. This supports previous evidence that the menopausal transition is a hormonally sensitive period in women's lives. To establish whether phthalate exposure contributes to body weight changes associated with the menopausal transition, substantially more research is needed to corroborate our findings." @default.
• W3110714937 created "2020-12-21" @default.
• W3110714937 creator A5040949438 @default.
• W3110714937 creator A5049751624 @default.
• W3110714937 creator A5076258650 @default.
• W3110714937 creator A5081232189 @default.
• W3110714937 date "2021-03-01" @default.
• W3110714937 modified "2023-10-14" @default.
• W3110714937 title "Phthalate exposures and one-year change in body mass index across the menopausal transition" @default.
• W3110714937 cites W1127139512 @default.
• W3110714937 cites W1972861639 @default.
• W3110714937 cites W1977978620 @default.
• W3110714937 cites W1982040808 @default.
• W3110714937 cites W1984486655 @default.
• W3110714937 cites W1984634361 @default.
• W3110714937 cites W1987452241 @default.
• W3110714937 cites W1987956232 @default.
• W3110714937 cites W1997777981 @default.
• W3110714937 cites W2007102917 @default.
• W3110714937 cites W2019913219 @default.
• W3110714937 cites W2042021834 @default.
• W3110714937 cites W2042138395 @default.
• W3110714937 cites W2056250382 @default.
• W3110714937 cites W2062594082 @default.
• W3110714937 cites W2064516418 @default.
• W3110714937 cites W2068576828 @default.
• W3110714937 cites W2069088947 @default.
• W3110714937 cites W2071133410 @default.
• W3110714937 cites W2078036688 @default.
• W3110714937 cites W2097049516 @default.
• W3110714937 cites W2113576333 @default.
• W3110714937 cites W2125492239 @default.
• W3110714937 cites W2136853165 @default.
• W3110714937 cites W2148619299 @default.
• W3110714937 cites W2151063137 @default.
• W3110714937 cites W2152718345 @default.
• W3110714937 cites W2155103683 @default.
• W3110714937 cites W2159145289 @default.
• W3110714937 cites W2161378952 @default.
• W3110714937 cites W2297296195 @default.
• W3110714937 cites W2345620911 @default.
• W3110714937 cites W2510411424 @default.
• W3110714937 cites W2520859925 @default.
• W3110714937 cites W2560630257 @default.
• W3110714937 cites W2576536258 @default.
• W3110714937 cites W2592439029 @default.
• W3110714937 cites W2619745907 @default.
• W3110714937 cites W2745648753 @default.
• W3110714937 cites W2753428410 @default.
• W3110714937 cites W2759588044 @default.
• W3110714937 cites W2769755799 @default.
• W3110714937 cites W2789376224 @default.
• W3110714937 cites W2791795490 @default.
• W3110714937 cites W2807404220 @default.
• W3110714937 cites W2886284196 @default.
• W3110714937 cites W2892136603 @default.
• W3110714937 cites W2901473182 @default.
• W3110714937 cites W2916179744 @default.
• W3110714937 cites W2930038248 @default.
• W3110714937 cites W2934998818 @default.
• W3110714937 cites W2970407502 @default.
• W3110714937 cites W3036961103 @default.
• W3110714937 cites W4294553991 @default.
• W3110714937 doi "https://doi.org/10.1016/j.envres.2020.110598" @default.
• W3110714937 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7946761" @default.
• W3110714937 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33307086" @default.
• W3110714937 hasPublicationYear "2021" @default.
• W3110714937 type Work @default.
• W3110714937 sameAs 3110714937 @default.
• W3110714937 citedByCount "8" @default.
• W3110714937 countsByYear W31107149372022 @default.
• W3110714937 countsByYear W31107149372023 @default.
• W3110714937 crossrefType "journal-article" @default.
• W3110714937 hasAuthorship W3110714937A5040949438 @default.
• W3110714937 hasAuthorship W3110714937A5049751624 @default.
• W3110714937 hasAuthorship W3110714937A5076258650 @default.
• W3110714937 hasAuthorship W3110714937A5081232189 @default.
• W3110714937 hasBestOaLocation W31107149371 @default.
• W3110714937 hasConcept C134018914 @default.
• W3110714937 hasConcept C178790620 @default.
• W3110714937 hasConcept C185592680 @default.
• W3110714937 hasConcept C2776481364 @default.
• W3110714937 hasConcept C2777414220 @default.
• W3110714937 hasConcept C2780221984 @default.
• W3110714937 hasConcept C2781005124 @default.
• W3110714937 hasConcept C42407357 @default.
• W3110714937 hasConcept C58968531 @default.
• W3110714937 hasConcept C71924100 @default.
• W3110714937 hasConceptScore W3110714937C134018914 @default.
• W3110714937 hasConceptScore W3110714937C178790620 @default.
• W3110714937 hasConceptScore W3110714937C185592680 @default.
• W3110714937 hasConceptScore W3110714937C2776481364 @default.
• W3110714937 hasConceptScore W3110714937C2777414220 @default.
• W3110714937 hasConceptScore W3110714937C2780221984 @default.
• W3110714937 hasConceptScore W3110714937C2781005124 @default.
• W3110714937 hasConceptScore W3110714937C42407357 @default.
• W3110714937 hasConceptScore W3110714937C58968531 @default.
• W3110714937 hasConceptScore W3110714937C71924100 @default.

• next