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• W3110777230 abstract "Gastric cancer (GC) is a type of malignant cancer with a poor prognosis. The iron's metabolism plays an important role in the process of GC. The aim of this study was to evaluate the effectiveness of SLC22A17, associated with iron metabolism, in predicting the prognosis of GC patients.We analyzed genes related to iron metabolism of gastric cancer mRNA-seq data from TCGA database. We identified an iron metabolism-related SLC22A17 as an independent prognostic factor using univariate and multivariate Cox regression analysis.Further research showed that SLC22A17 was related with many pathways involved in the process of gastric cancer, and the expression was associated with diverse cancer-infiltrating immune cells. The expression of SLC22A17 was associated with T (Topography).We validated that SLC22A17 associated with iron metabolism could serve as a prognostic biomarker for GC patients." @default.
• W3110777230 created "2020-12-21" @default.
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• W3110777230 date "2020-12-01" @default.
• W3110777230 modified "2023-10-18" @default.
• W3110777230 title "<p>An Iron Metabolism-Related <em>SLC22A17</em> for the Prognostic Value of Gastric Cancer</p>" @default.
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• W3110777230 doi "https://doi.org/10.2147/ott.s287811" @default.
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