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- W3110837306 abstract "Abstract Time-reversal (TR) is a known wideband array beam-forming technique that has been suggested as a treatment planning alternative in deep microwave hyperthermia for cancer treatment. While the aim in classic TR is to focus the energy at a specific point within the target, no assumptions are made on secondary lobes that might arise in the healthy tissues. These secondary lobes, together with tissue heterogeneity, may result in hot-spots (HSs), which are known to limit the efficiency of the thermal dose delivery to the tumor. This paper proposes a novel wideband TR focusing method that iteratively shifts the focus away from HSs and towards cold-spots from an initial TR solution, a procedure that improves tumor coverage and reduces HSs. We verify this method on two different applicator topologies and several target volume configurations. The algorithm is deterministic and runs within seconds, enabling its use for real-time applications. At the same time, it yields results comparable to those obtained with global stochastic optimizers such as Particle Swarm." @default.
- W3110837306 created "2020-12-21" @default.
- W3110837306 creator A5006432011 @default.
- W3110837306 creator A5088682951 @default.
- W3110837306 date "2021-02-10" @default.
- W3110837306 modified "2023-10-04" @default.
- W3110837306 title "Iterative time-reversal for multi-frequency hyperthermia" @default.
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- W3110837306 doi "https://doi.org/10.1088/1361-6560/abd41a" @default.
- W3110837306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33326945" @default.
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