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- W3111099436 abstract "Abstract Biomedical applications of magnetic resonance spectroscopy (MRS) and Magnetic Resonance Imaging (MRI) mainly study the signals originating from proton spins (1H). In the human body, the proton MR signals arise predominantly from water-based aqueous tissues and fat-based adipose tissues. Owing to differences in their local chemical environments, proton signals from water-based and fat-based tissues exhibit different MR properties, including for example T1 relaxation, T2 (and T 2 * ) relaxation, chemical shift, and diffusion rates. As a result, fat often appears bright and can cause chemical-shift artifacts in MRI, and thus fat suppression has been an extensively studied topic in conventional qualitative MRI. At the same time, these differences in MR properties between water and fat make it possible to identify and quantify the amount of fat versus water in vivo, which provides a host of unique quantitative MRI parameters to measure the fat distribution and study the progression of metabolic diseases. In particular, the proton-density fat fraction measured by MRS or chemical-shift-encoded MRI is now an accepted imaging biomarker of fat content. This chapter provides an overview of the MR techniques used to quantify fat in the human body, spanning from the basic concepts for distinguishing fat from water to advanced state-of-the-art methods for quantifying fat. The MRS and MRI pulse sequences, acquisition strategies, and signal models for fat quantification will be presented." @default.
- W3111099436 created "2020-12-21" @default.
- W3111099436 creator A5064950342 @default.
- W3111099436 creator A5089387605 @default.
- W3111099436 date "2020-01-01" @default.
- W3111099436 modified "2023-10-17" @default.
- W3111099436 title "Fat Quantification Techniques" @default.
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