FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111100013> ?p ?o ?g. }

• W3111100013 endingPage "372" @default.
• W3111100013 startingPage "363" @default.
• W3111100013 abstract "Abstract Women are anticipated to go through more than two rounds of cervical screening in their lifetime. Human papillomavirus (HPV) testing is increasingly used as the primary cervical cancer screening test. However, triage strategies for HPV-positive women were usually evaluated at baseline screening. We assessed the effect of sequential rounds of cervical screening on several algorithms for HPV triage. A total of 1,997 women ages 35–45 years were enrolled in 1999 in Shanxi, P.R. China and followed up three times at approximately 5-year intervals. Cervical intraepithelial neoplasia (CIN) grade 2 or worse (CIN2+) prevalence by prior HPV results and performance of 12 triage algorithms with cytology, genotyping, and prior HPV were examined among 229 HPV-positive women at the fourth round. CIN2+ prevalence varied from 56.5% (95% confidence interval, 36.8%–74.4%) following 15 years HPV persistence to 3.5% (1.2%–9.9%) with an incident HPV within 15 years. Triage with cytology (with threshold of atypical squamous cells of undetermined significance) yielded positive predictive value (PPV) of 21.4% (13.8%–29.0%), entailing immediate colposcopic referral, and negative predictive value (NPV) of 97.4% (94.6%–100%), permitting retesting at short intervals. Triage with genotyping (16/18/31/33/45/52/58) or prior HPV results showed comparable performance with cytology. Among 11 triage algorithms with similar NPV to cytology, triage with prior HPV results and reflex genotyping (16/18) achieved highest PPV of 28.9% (18.8%–39.1%) and lowest colposcopy referral of 33.2% (27.4%–39.5%). HPV persistence across rounds is an effective risk stratifier in HPV-positive women. Mainstream cytology and genotyping, with or without consideration of prior HPV results, remain effective for HPV triage at fourth round. Prevention Relevance: The study highlights the sustained effectiveness of mainstream HPV triage methods, such as cytology and genotyping, after sequential rounds of cervical screening. It also suggests that use of HPV persistence across rounds can improve management of HPV-positive women in cervical cancer screening." @default.
• W3111100013 created "2020-12-21" @default.
• W3111100013 creator A5009744576 @default.
• W3111100013 creator A5020789868 @default.
• W3111100013 creator A5021979312 @default.
• W3111100013 creator A5023533442 @default.
• W3111100013 creator A5025345555 @default.
• W3111100013 creator A5031132768 @default.
• W3111100013 creator A5046143675 @default.
• W3111100013 creator A5048610843 @default.
• W3111100013 creator A5062018101 @default.
• W3111100013 creator A5078128438 @default.
• W3111100013 creator A5082077174 @default.
• W3111100013 date "2021-03-01" @default.
• W3111100013 modified "2023-10-16" @default.
• W3111100013 title "Effect of Sequential Rounds of Cervical Cancer Screening on Management of HPV-positive Women: A 15-year Population-based Cohort Study from China" @default.
• W3111100013 cites W1972424675 @default.
• W3111100013 cites W1981500683 @default.
• W3111100013 cites W2036087634 @default.
• W3111100013 cites W2039633905 @default.
• W3111100013 cites W2058444448 @default.
• W3111100013 cites W2061935051 @default.
• W3111100013 cites W2066009669 @default.
• W3111100013 cites W2096733107 @default.
• W3111100013 cites W2134674929 @default.
• W3111100013 cites W2139736159 @default.
• W3111100013 cites W2141319143 @default.
• W3111100013 cites W2144119531 @default.
• W3111100013 cites W2158758816 @default.
• W3111100013 cites W2158872827 @default.
• W3111100013 cites W2462954037 @default.
• W3111100013 cites W2526320839 @default.
• W3111100013 cites W2528966414 @default.
• W3111100013 cites W2530128350 @default.
• W3111100013 cites W2551830992 @default.
• W3111100013 cites W2618189756 @default.
• W3111100013 cites W2732959750 @default.
• W3111100013 cites W2770664071 @default.
• W3111100013 cites W2787965113 @default.
• W3111100013 cites W2811260298 @default.
• W3111100013 cites W2904905411 @default.
• W3111100013 cites W2906060544 @default.
• W3111100013 cites W2914625292 @default.
• W3111100013 cites W2936710467 @default.
• W3111100013 cites W2978990098 @default.
• W3111100013 cites W2987372192 @default.
• W3111100013 cites W3001868766 @default.
• W3111100013 cites W3014290825 @default.
• W3111100013 cites W3014715123 @default.
• W3111100013 cites W3015070206 @default.
• W3111100013 cites W3015112546 @default.
• W3111100013 cites W3015153366 @default.
• W3111100013 cites W4376522311 @default.
• W3111100013 cites W2893704974 @default.
• W3111100013 doi "https://doi.org/10.1158/1940-6207.capr-20-0456" @default.
• W3111100013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33303694" @default.
• W3111100013 hasPublicationYear "2021" @default.
• W3111100013 type Work @default.
• W3111100013 sameAs 3111100013 @default.
• W3111100013 citedByCount "1" @default.
• W3111100013 countsByYear W31111000132021 @default.
• W3111100013 crossrefType "journal-article" @default.
• W3111100013 hasAuthorship W3111100013A5009744576 @default.
• W3111100013 hasAuthorship W3111100013A5020789868 @default.
• W3111100013 hasAuthorship W3111100013A5021979312 @default.
• W3111100013 hasAuthorship W3111100013A5023533442 @default.
• W3111100013 hasAuthorship W3111100013A5025345555 @default.
• W3111100013 hasAuthorship W3111100013A5031132768 @default.
• W3111100013 hasAuthorship W3111100013A5046143675 @default.
• W3111100013 hasAuthorship W3111100013A5048610843 @default.
• W3111100013 hasAuthorship W3111100013A5062018101 @default.
• W3111100013 hasAuthorship W3111100013A5078128438 @default.
• W3111100013 hasAuthorship W3111100013A5082077174 @default.
• W3111100013 hasBestOaLocation W31111000131 @default.
• W3111100013 hasConcept C104317684 @default.
• W3111100013 hasConcept C121608353 @default.
• W3111100013 hasConcept C126322002 @default.
• W3111100013 hasConcept C131872663 @default.
• W3111100013 hasConcept C135763542 @default.
• W3111100013 hasConcept C142724271 @default.
• W3111100013 hasConcept C18823058 @default.
• W3111100013 hasConcept C194828623 @default.
• W3111100013 hasConcept C2776117191 @default.
• W3111100013 hasConcept C2776135927 @default.
• W3111100013 hasConcept C2777120189 @default.
• W3111100013 hasConcept C2777343196 @default.
• W3111100013 hasConcept C2778220009 @default.
• W3111100013 hasConcept C2780647465 @default.
• W3111100013 hasConcept C2908647359 @default.
• W3111100013 hasConcept C29456083 @default.
• W3111100013 hasConcept C31467283 @default.
• W3111100013 hasConcept C44249647 @default.
• W3111100013 hasConcept C512399662 @default.
• W3111100013 hasConcept C55493867 @default.
• W3111100013 hasConcept C71924100 @default.
• W3111100013 hasConcept C86803240 @default.
• W3111100013 hasConcept C99454951 @default.
• W3111100013 hasConceptScore W3111100013C104317684 @default.

• next