FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111188511> ?p ?o ?g. }

• W3111188511 abstract "Abstract BACKGROUND To evaluate the impact of adjuvant postoperative radiotherapy (PORT) in adult WHO grade II–III intracranial ependymoma (IEPN). METHODS A total of 172 pathologically confirmed adult grade II–III IEPN patients from 12 institutions were eligible. Of them, 106 (61.6%) and 66 (38.4%) patients were grade II and III, respectively. For grade II and III IEPNs, 51 (48.1%) and 59 (89.4%) patients received PORT, respectively. The median dose to the primary tumor bed was 54.0 Gy and 59.4 Gy for grade II and III patients, respectively. The prognostic impact of sex, age, performance, WHO grade, location, size, surgical extent, and PORT on local control (LC), progression-free survival (PFS), and overall survival (OS) were evaluated by univariate and multivariate analysis. RESULTS The median follow-up period for survivors was 88.1 months. The 5-/10-year LC, PFS, and OS rates were 64.8%/54.0%, 56.4%/44.8%, and 76.6%/71.0%, respectively. On multivariate analysis, adjuvant PORT significantly improved LC (P=0.002), PFS (P=0.002), and OS (P=0.043). Older age (P&lt; 0.001), WHO grade III (P&lt; 0.001), larger tumor size (P=0.004), and lesser surgical extent (P&lt; 0.001) were also negative factors for OS. Adjuvant PORT also improved LC (P=0.010), PFS (P=0.007), and OS (P=0.069) on multivariate analysis for grade II IEPNs. CONCLUSION This multicenter retrospective study supports the role of adjuvant PORT in terms of disease control and survival in adult grade II–III IEPNs. Prospective randomized trials focused on individualized treatment based on molecular subtypes is warranted." @default.
• W3111188511 created "2020-12-21" @default.
• W3111188511 creator A5001896186 @default.
• W3111188511 creator A5002576941 @default.
• W3111188511 creator A5008217338 @default.
• W3111188511 creator A5008228126 @default.
• W3111188511 creator A5012842975 @default.
• W3111188511 creator A5012843877 @default.
• W3111188511 creator A5016142912 @default.
• W3111188511 creator A5018929039 @default.
• W3111188511 creator A5021105669 @default.
• W3111188511 creator A5022733670 @default.
• W3111188511 creator A5025322881 @default.
• W3111188511 creator A5027678674 @default.
• W3111188511 creator A5029749234 @default.
• W3111188511 creator A5036838741 @default.
• W3111188511 creator A5069821851 @default.
• W3111188511 creator A5078389794 @default.
• W3111188511 creator A5078809545 @default.
• W3111188511 creator A5079052740 @default.
• W3111188511 creator A5079181340 @default.
• W3111188511 creator A5084782886 @default.
• W3111188511 date "2020-11-01" @default.
• W3111188511 modified "2023-09-23" @default.
• W3111188511 title "RADT-35. POSTOPERATIVE RADIOTHERAPY FOR WHO GRADE II–III INTRACRANIAL EPENDYMOMA IN ADULTS: AN INTERGROUP COLLABORATIVE STUDY (KROG 18-06/KNOG 18-01)" @default.
• W3111188511 doi "https://doi.org/10.1093/neuonc/noaa215.788" @default.
• W3111188511 hasPublicationYear "2020" @default.
• W3111188511 type Work @default.
• W3111188511 sameAs 3111188511 @default.
• W3111188511 citedByCount "0" @default.
• W3111188511 crossrefType "journal-article" @default.
• W3111188511 hasAuthorship W3111188511A5001896186 @default.
• W3111188511 hasAuthorship W3111188511A5002576941 @default.
• W3111188511 hasAuthorship W3111188511A5008217338 @default.
• W3111188511 hasAuthorship W3111188511A5008228126 @default.
• W3111188511 hasAuthorship W3111188511A5012842975 @default.
• W3111188511 hasAuthorship W3111188511A5012843877 @default.
• W3111188511 hasAuthorship W3111188511A5016142912 @default.
• W3111188511 hasAuthorship W3111188511A5018929039 @default.
• W3111188511 hasAuthorship W3111188511A5021105669 @default.
• W3111188511 hasAuthorship W3111188511A5022733670 @default.
• W3111188511 hasAuthorship W3111188511A5025322881 @default.
• W3111188511 hasAuthorship W3111188511A5027678674 @default.
• W3111188511 hasAuthorship W3111188511A5029749234 @default.
• W3111188511 hasAuthorship W3111188511A5036838741 @default.
• W3111188511 hasAuthorship W3111188511A5069821851 @default.
• W3111188511 hasAuthorship W3111188511A5078389794 @default.
• W3111188511 hasAuthorship W3111188511A5078809545 @default.
• W3111188511 hasAuthorship W3111188511A5079052740 @default.
• W3111188511 hasAuthorship W3111188511A5079181340 @default.
• W3111188511 hasAuthorship W3111188511A5084782886 @default.
• W3111188511 hasBestOaLocation W31111885111 @default.
• W3111188511 hasConcept C119599485 @default.
• W3111188511 hasConcept C121608353 @default.
• W3111188511 hasConcept C126322002 @default.
• W3111188511 hasConcept C127413603 @default.
• W3111188511 hasConcept C141071460 @default.
• W3111188511 hasConcept C144301174 @default.
• W3111188511 hasConcept C2777863537 @default.
• W3111188511 hasConcept C2777982462 @default.
• W3111188511 hasConcept C2781432949 @default.
• W3111188511 hasConcept C3018454096 @default.
• W3111188511 hasConcept C3019894029 @default.
• W3111188511 hasConcept C32802771 @default.
• W3111188511 hasConcept C38180746 @default.
• W3111188511 hasConcept C509974204 @default.
• W3111188511 hasConcept C71924100 @default.
• W3111188511 hasConcept C90924648 @default.
• W3111188511 hasConceptScore W3111188511C119599485 @default.
• W3111188511 hasConceptScore W3111188511C121608353 @default.
• W3111188511 hasConceptScore W3111188511C126322002 @default.
• W3111188511 hasConceptScore W3111188511C127413603 @default.
• W3111188511 hasConceptScore W3111188511C141071460 @default.
• W3111188511 hasConceptScore W3111188511C144301174 @default.
• W3111188511 hasConceptScore W3111188511C2777863537 @default.
• W3111188511 hasConceptScore W3111188511C2777982462 @default.
• W3111188511 hasConceptScore W3111188511C2781432949 @default.
• W3111188511 hasConceptScore W3111188511C3018454096 @default.
• W3111188511 hasConceptScore W3111188511C3019894029 @default.
• W3111188511 hasConceptScore W3111188511C32802771 @default.
• W3111188511 hasConceptScore W3111188511C38180746 @default.
• W3111188511 hasConceptScore W3111188511C509974204 @default.
• W3111188511 hasConceptScore W3111188511C71924100 @default.
• W3111188511 hasConceptScore W3111188511C90924648 @default.
• W3111188511 hasLocation W31111885111 @default.
• W3111188511 hasLocation W31111885112 @default.
• W3111188511 hasLocation W31111885113 @default.
• W3111188511 hasOpenAccess W3111188511 @default.
• W3111188511 hasPrimaryLocation W31111885111 @default.
• W3111188511 hasRelatedWork W10949566 @default.
• W3111188511 hasRelatedWork W12065771 @default.
• W3111188511 hasRelatedWork W12395923 @default.
• W3111188511 hasRelatedWork W5531945 @default.
• W3111188511 hasRelatedWork W5806089 @default.
• W3111188511 hasRelatedWork W6215689 @default.
• W3111188511 hasRelatedWork W6374340 @default.
• W3111188511 hasRelatedWork W6550088 @default.
• W3111188511 hasRelatedWork W8512914 @default.
• W3111188511 hasRelatedWork W10924045 @default.
• W3111188511 isParatext "false" @default.

• next