Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111188919> ?p ?o ?g. }
- W3111188919 endingPage "247" @default.
- W3111188919 startingPage "233" @default.
- W3111188919 abstract "Circadian rhythms are 24-h cycles in physiology and behavior that occur in virtually all organisms. These processes are not simply driven by changes in the external environment as they persist under constant conditions, providing evidence for an internal biological clock. In mammals, this clock is located in the hypothalamic suprachiasmatic nuclei (SCN) and is based upon an intracellular mechanism composed of a transcriptional–translational feedback loop composed of a number of core clock genes. However, a clock is of no use unless it can be set to the correct time. The primary time cue for the molecular clock in the SCN is light detected by the eye. The photoreceptors involved in this process include the rods and cones that mediate vision, as well as the recently identified melanopsin-expressing photosensitive retinal ganglion cells (pRGCs). Light information is conveyed to the SCN via the retinohypothalamic tract, resulting in an intracellular signaling cascade which converges on cAMP-response elements in the promoters of several key clock genes. Over the last two decades a number of studies have investigated the transcriptional response of the SCN to light stimuli with the aim of further understanding these molecular signaling pathways. Here we provide an overview of these studies and provide protocols for studying the molecular responses to light in the SCN clock." @default.
- W3111188919 created "2020-12-21" @default.
- W3111188919 creator A5009326571 @default.
- W3111188919 creator A5066074861 @default.
- W3111188919 creator A5067384437 @default.
- W3111188919 creator A5078293727 @default.
- W3111188919 date "2020-12-08" @default.
- W3111188919 modified "2023-09-25" @default.
- W3111188919 title "Light Input to the Mammalian Circadian Clock" @default.
- W3111188919 cites W1507909762 @default.
- W3111188919 cites W1545062366 @default.
- W3111188919 cites W1587250362 @default.
- W3111188919 cites W161535444 @default.
- W3111188919 cites W1662741476 @default.
- W3111188919 cites W1794320447 @default.
- W3111188919 cites W1929552083 @default.
- W3111188919 cites W1965310675 @default.
- W3111188919 cites W1965843937 @default.
- W3111188919 cites W1967473768 @default.
- W3111188919 cites W1967534660 @default.
- W3111188919 cites W1970130379 @default.
- W3111188919 cites W1970355769 @default.
- W3111188919 cites W1983875092 @default.
- W3111188919 cites W1986608768 @default.
- W3111188919 cites W1992182952 @default.
- W3111188919 cites W1997718482 @default.
- W3111188919 cites W1998448534 @default.
- W3111188919 cites W2000631266 @default.
- W3111188919 cites W2002006123 @default.
- W3111188919 cites W2003302378 @default.
- W3111188919 cites W2009077913 @default.
- W3111188919 cites W2014028088 @default.
- W3111188919 cites W2014313900 @default.
- W3111188919 cites W2016027614 @default.
- W3111188919 cites W2017222418 @default.
- W3111188919 cites W2018885521 @default.
- W3111188919 cites W2022197238 @default.
- W3111188919 cites W2022442940 @default.
- W3111188919 cites W2022702024 @default.
- W3111188919 cites W2024493318 @default.
- W3111188919 cites W2026136324 @default.
- W3111188919 cites W2027071841 @default.
- W3111188919 cites W2028674633 @default.
- W3111188919 cites W2035352715 @default.
- W3111188919 cites W2035853180 @default.
- W3111188919 cites W2036024950 @default.
- W3111188919 cites W2045647450 @default.
- W3111188919 cites W2047331522 @default.
- W3111188919 cites W2048466060 @default.
- W3111188919 cites W2054821490 @default.
- W3111188919 cites W2057456046 @default.
- W3111188919 cites W2057522076 @default.
- W3111188919 cites W2058594012 @default.
- W3111188919 cites W2072018453 @default.
- W3111188919 cites W2072393773 @default.
- W3111188919 cites W2073148060 @default.
- W3111188919 cites W2076154095 @default.
- W3111188919 cites W2077081389 @default.
- W3111188919 cites W2078689239 @default.
- W3111188919 cites W2089747584 @default.
- W3111188919 cites W2095326601 @default.
- W3111188919 cites W2096882849 @default.
- W3111188919 cites W2100389191 @default.
- W3111188919 cites W2105573565 @default.
- W3111188919 cites W2106496774 @default.
- W3111188919 cites W2107083462 @default.
- W3111188919 cites W2110209988 @default.
- W3111188919 cites W2113297137 @default.
- W3111188919 cites W2113671711 @default.
- W3111188919 cites W2123584715 @default.
- W3111188919 cites W2133668388 @default.
- W3111188919 cites W2133918896 @default.
- W3111188919 cites W2143210222 @default.
- W3111188919 cites W2147949992 @default.
- W3111188919 cites W2151046665 @default.
- W3111188919 cites W2151468131 @default.
- W3111188919 cites W2156902902 @default.
- W3111188919 cites W2158698831 @default.
- W3111188919 cites W2160214073 @default.
- W3111188919 cites W2167008303 @default.
- W3111188919 cites W2170538407 @default.
- W3111188919 cites W2233039400 @default.
- W3111188919 cites W2408968402 @default.
- W3111188919 cites W2415509130 @default.
- W3111188919 cites W2467950790 @default.
- W3111188919 cites W4245011475 @default.
- W3111188919 doi "https://doi.org/10.1007/978-1-0716-0381-9_18" @default.
- W3111188919 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33284449" @default.
- W3111188919 hasPublicationYear "2020" @default.
- W3111188919 type Work @default.
- W3111188919 sameAs 3111188919 @default.
- W3111188919 citedByCount "7" @default.
- W3111188919 countsByYear W31111889192021 @default.
- W3111188919 countsByYear W31111889192022 @default.
- W3111188919 countsByYear W31111889192023 @default.
- W3111188919 crossrefType "book-chapter" @default.
- W3111188919 hasAuthorship W3111188919A5009326571 @default.
- W3111188919 hasAuthorship W3111188919A5066074861 @default.