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- W3111257029 endingPage "43370" @default.
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- W3111257029 abstract "Nitrogen-containing heterocycles represent a major source of pharmacological probes and drug candidates. To extend their molecular diversity and their potential biological activities, it is of importance to design and synthesize new N-heterocyclic scaffolds. Therefore, aza-diketopiperazines (aza-DKPs), the aza analogues of well-known 2,5-diketopiperazines (DKPs), emerged as a promising new scaffold. Although the first synthesis of an aza-DKP dates from 1951, significant developments have been made during the last decade. This feature article summarizes the different synthetic strategies to access and functionalise aza-DKPs. Their biological properties and potential applications in medicinal chemistry and drug discovery are discussed as well." @default.
- W3111257029 created "2020-12-21" @default.
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- W3111257029 date "2020-01-01" @default.
- W3111257029 modified "2023-10-16" @default.
- W3111257029 title "Three cheers for nitrogen: aza-DKPs, the aza analogues of 2,5-diketopiperazines" @default.
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- W3111257029 doi "https://doi.org/10.1039/d0ra09457a" @default.
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