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- W3111609308 abstract "Abstract Hypochlorous acid (HOCl) plays a crucial role in many physiological processes and is widely used as bleach, deodorant and fungicide. In this work, we designed an amphiphilic hydrazone fluorescent molecule THG‐1 containing hydrophilic sugar units and hydrophobic tetraphenylethylene unit for ratiometric detection of HOCl with high sensitivity and excellent selectivity based on HOCl‐triggered hydrolyzation reaction and aggregation‐induced emission (AIE) effect. The detection mechanism was verified by liquid chromatograph mass spectrometry experiments and scanning electron microscope (SEM) tests. Contrast experiments revealed that the numbers of lactose unit and hydrazone linker were essential for assembly of THG‐1 and detection of HOCl. In addition, THG‐1 was successfully used for imaging of exogenous and endogenous HOCl in living cells." @default.
- W3111609308 created "2020-12-21" @default.
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- W3111609308 date "2021-01-12" @default.
- W3111609308 modified "2023-10-17" @default.
- W3111609308 title "Assembly of Water‐soluble AIE‐active Fluorescent Organic Nanoparticles for Ratiometric Detection of Hypochlorite in Living Cells" @default.
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- W3111609308 doi "https://doi.org/10.1002/asia.202001325" @default.
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