FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111702326> ?p ?o ?g. }

• W3111702326 abstract "Abstract INTRODUCTION Retroperitoneal leiomyosarcoma is a relatively rare disease, with infrequent metastatic spread to the CNS. We present the first report of radiosurgical treatment of this disease. METHODS A 49-year-old woman developed leiomyosarcoma of the inferior vena cava and retroperitoneum with lung metastases on diagnosis. Following multiple courses of systemic and operative treatment, she developed a tender ulcerating mass in the left upper maxillary incisor associated with numbness along the upper gum, lip, and premaxillary area. CT revealed a 3.0 cm left posterior alveolar ridge gum lesion with bone invasion, for which she elected to undergo palliative radiation therapy (30 Gy in 10 fractions). Due to potential maxillary nerve involvement altering the intended radiation therapy treatment fields, an orbit/face MRI was performed to better delineate the lesion. On this MRI, two frontal lobe lesions were visualized; subsequent dedicated brain MRI revealed a total of five metastases (0.9 cm right superior frontal gyrus, 0.9 cm left middle frontal gyrus, 0.9 cm right postcentral gyrus, 0.7 cm right occipital, and 1.6 cm left occipital). Consequently, the decision was made to treat the brain metastases with linear accelerator (LINAC) stereotactic radiosurgery (SRS) to allow simultaneous treatment of the maxillary lesion and brain metastases. RESULTS A single CT simulation was performed for her intracranial and extracranial disease, using the Encompass face mask to allow for simultaneous head immobilization and optimal SRS targeting accuracy. LINAC SRS was delivered simultaneously during maxillary lesion radiation therapy to all five lesions (22 Gy to the 80% isodose line) in a single fraction with a 0.2 cm planning target volume (PTV) margin for each lesion. CONCLUSIONS The first reported case of metastatic retroperitoneal leiomyosarcoma brain metastases treated with SRS demonstrates the flexibility of LINAC (rather than Gamma Knife) SRS in allowing for simultaneous treatment of intracranial and extracranial metastatic disease." @default.
• W3111702326 created "2020-12-21" @default.
• W3111702326 creator A5004834792 @default.
• W3111702326 creator A5015338018 @default.
• W3111702326 creator A5027841480 @default.
• W3111702326 creator A5037724529 @default.
• W3111702326 date "2020-11-01" @default.
• W3111702326 modified "2023-10-14" @default.
• W3111702326 title "RADT-43. TREATMENT OF RETROPERITONEAL LEIOMYOSARCOMA BRAIN METASTASES WITH STEREOTACTIC RADIOSURGERY" @default.
• W3111702326 doi "https://doi.org/10.1093/neuonc/noaa215.796" @default.
• W3111702326 hasPublicationYear "2020" @default.
• W3111702326 type Work @default.
• W3111702326 sameAs 3111702326 @default.
• W3111702326 citedByCount "0" @default.
• W3111702326 crossrefType "journal-article" @default.
• W3111702326 hasAuthorship W3111702326A5004834792 @default.
• W3111702326 hasAuthorship W3111702326A5015338018 @default.
• W3111702326 hasAuthorship W3111702326A5027841480 @default.
• W3111702326 hasAuthorship W3111702326A5037724529 @default.
• W3111702326 hasBestOaLocation W31117023261 @default.
• W3111702326 hasConcept C126838900 @default.
• W3111702326 hasConcept C141071460 @default.
• W3111702326 hasConcept C2780387249 @default.
• W3111702326 hasConcept C2781156865 @default.
• W3111702326 hasConcept C2989005 @default.
• W3111702326 hasConcept C509974204 @default.
• W3111702326 hasConcept C71924100 @default.
• W3111702326 hasConceptScore W3111702326C126838900 @default.
• W3111702326 hasConceptScore W3111702326C141071460 @default.
• W3111702326 hasConceptScore W3111702326C2780387249 @default.
• W3111702326 hasConceptScore W3111702326C2781156865 @default.
• W3111702326 hasConceptScore W3111702326C2989005 @default.
• W3111702326 hasConceptScore W3111702326C509974204 @default.
• W3111702326 hasConceptScore W3111702326C71924100 @default.
• W3111702326 hasLocation W31117023261 @default.
• W3111702326 hasLocation W31117023262 @default.
• W3111702326 hasLocation W31117023263 @default.
• W3111702326 hasOpenAccess W3111702326 @default.
• W3111702326 hasPrimaryLocation W31117023261 @default.
• W3111702326 hasRelatedWork W12930299 @default.
• W3111702326 hasRelatedWork W13130823 @default.
• W3111702326 hasRelatedWork W1367007 @default.
• W3111702326 hasRelatedWork W13842510 @default.
• W3111702326 hasRelatedWork W1442698 @default.
• W3111702326 hasRelatedWork W17845636 @default.
• W3111702326 hasRelatedWork W20393887 @default.
• W3111702326 hasRelatedWork W7089652 @default.
• W3111702326 hasRelatedWork W7873026 @default.
• W3111702326 hasRelatedWork W7920107 @default.
• W3111702326 isParatext "false" @default.
• W3111702326 isRetracted "false" @default.
• W3111702326 magId "3111702326" @default.
• W3111702326 workType "article" @default.