FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111771842> ?p ?o ?g. }

• W3111771842 endingPage "116358" @default.
• W3111771842 startingPage "116358" @default.
• W3111771842 abstract "Polyaromatic phenanthrene (Phe) and benzo[a]pyrene (BaP) are highly toxic, mutagenic, and carcinogenic contaminants widely dispersed in nature, including saline environments. Polyextremotolerant Rhodotorula mucilaginosa EXF-1630, isolated from Arctic sea ice, was grown on a huge concentration range -10 to 500 ppm- of Phe and BaP as sole carbon sources at hypersaline conditions (1 M NaCl). Selected polycyclic aromatic hydrocarbons (PAHs) supported growth as well as glucose, even at high PAH concentrations. Initially, up to 40% of Phe and BaP were adsorbed, followed by biodegradation, resulting in 80% removal in 10 days. While extracellular laccase, peroxidase, and un-specific peroxygenase activities were not detected, NADPH-cytochrome c reductase activity peaked at 4 days. The successful removal of PAHs and the absence of toxic metabolites were confirmed by toxicological tests on moss Physcomitrium patens, bacterium Aliivibrio fischeri, human erythrocytes, and pulmonary epithelial cells (A549). Metabolic profiles were determined at the midpoint of the biodegradation exponential phase, with added Phe and BaP (100 ppm) and 1 M NaCl. Different hydroxylated products were found in the culture medium, while the conjugative metabolite 1-phenanthryl-β-D-glucopyranose was detected in the medium and in the cells. Transcriptome analysis resulted in 870 upregulated and 2,288 downregulated transcripts on PAHs, in comparison to glucose. Genomic mining of 61 available yeast genomes showed a widespread distribution of 31 xenobiotic degradation pathways in different yeast lineages. Two distributions with similar metabolic capacities included black yeasts and mainly members of the Sporidiobolaceae family (including EXF-1630), respectively. This is the first work describing a metabolic profile and transcriptomic analysis of PAH degradation by yeast." @default.
• W3111771842 created "2020-12-21" @default.
• W3111771842 creator A5006000287 @default.
• W3111771842 creator A5016348484 @default.
• W3111771842 creator A5026497349 @default.
• W3111771842 creator A5027121172 @default.
• W3111771842 creator A5040380707 @default.
• W3111771842 creator A5045898321 @default.
• W3111771842 creator A5050332717 @default.
• W3111771842 creator A5055717756 @default.
• W3111771842 creator A5071934786 @default.
• W3111771842 creator A5072874717 @default.
• W3111771842 creator A5076919300 @default.
• W3111771842 creator A5086165889 @default.
• W3111771842 date "2021-02-01" @default.
• W3111771842 modified "2023-10-04" @default.
• W3111771842 title "Tracking gene expression, metabolic profiles, and biochemical analysis in the halotolerant basidiomycetous yeast Rhodotorula mucilaginosa EXF-1630 during benzo[a]pyrene and phenanthrene biodegradation under hypersaline conditions" @default.
• W3111771842 cites W1204757663 @default.
• W3111771842 cites W1882418526 @default.
• W3111771842 cites W1963957860 @default.
• W3111771842 cites W1965319833 @default.
• W3111771842 cites W1965381930 @default.
• W3111771842 cites W1971904157 @default.
• W3111771842 cites W1972552973 @default.
• W3111771842 cites W1973436365 @default.
• W3111771842 cites W1976287915 @default.
• W3111771842 cites W2006281639 @default.
• W3111771842 cites W2006683077 @default.
• W3111771842 cites W2015922424 @default.
• W3111771842 cites W2019009315 @default.
• W3111771842 cites W2028944714 @default.
• W3111771842 cites W2031611770 @default.
• W3111771842 cites W2039521726 @default.
• W3111771842 cites W2051112149 @default.
• W3111771842 cites W2056129150 @default.
• W3111771842 cites W2062337731 @default.
• W3111771842 cites W2064057547 @default.
• W3111771842 cites W2086463790 @default.
• W3111771842 cites W2126419817 @default.
• W3111771842 cites W2131271579 @default.
• W3111771842 cites W2131388529 @default.
• W3111771842 cites W2160378127 @default.
• W3111771842 cites W2165531848 @default.
• W3111771842 cites W2166320135 @default.
• W3111771842 cites W2179438025 @default.
• W3111771842 cites W2183542825 @default.
• W3111771842 cites W2199532495 @default.
• W3111771842 cites W2223777707 @default.
• W3111771842 cites W2276880823 @default.
• W3111771842 cites W2283078802 @default.
• W3111771842 cites W2301086619 @default.
• W3111771842 cites W2323326409 @default.
• W3111771842 cites W2341119117 @default.
• W3111771842 cites W2413209982 @default.
• W3111771842 cites W2517745388 @default.
• W3111771842 cites W2537383768 @default.
• W3111771842 cites W2558686039 @default.
• W3111771842 cites W2619395705 @default.
• W3111771842 cites W2621137997 @default.
• W3111771842 cites W2623597117 @default.
• W3111771842 cites W2625541407 @default.
• W3111771842 cites W2731745619 @default.
• W3111771842 cites W2741499161 @default.
• W3111771842 cites W2753629559 @default.
• W3111771842 cites W2757514175 @default.
• W3111771842 cites W2760667690 @default.
• W3111771842 cites W2761876220 @default.
• W3111771842 cites W2781723982 @default.
• W3111771842 cites W2782395996 @default.
• W3111771842 cites W2790423458 @default.
• W3111771842 cites W2791727616 @default.
• W3111771842 cites W2792235909 @default.
• W3111771842 cites W2798064943 @default.
• W3111771842 cites W2799431084 @default.
• W3111771842 cites W2886954699 @default.
• W3111771842 cites W2888718285 @default.
• W3111771842 cites W2899763402 @default.
• W3111771842 cites W2912329112 @default.
• W3111771842 cites W2914273932 @default.
• W3111771842 cites W2964276516 @default.
• W3111771842 cites W2964452263 @default.
• W3111771842 cites W2969443468 @default.
• W3111771842 cites W2971591608 @default.
• W3111771842 cites W2979308659 @default.
• W3111771842 cites W2991910555 @default.
• W3111771842 cites W2997127484 @default.
• W3111771842 cites W3001485304 @default.
• W3111771842 cites W3006824577 @default.
• W3111771842 cites W3035885497 @default.
• W3111771842 cites W3049382557 @default.
• W3111771842 cites W930471266 @default.
• W3111771842 doi "https://doi.org/10.1016/j.envpol.2020.116358" @default.
• W3111771842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33385892" @default.
• W3111771842 hasPublicationYear "2021" @default.
• W3111771842 type Work @default.
• W3111771842 sameAs 3111771842 @default.
• W3111771842 citedByCount "16" @default.
• W3111771842 countsByYear W31117718422021 @default.

• next