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- W3111821971 abstract "In this work, an enzyme-free recycling amplification-based sensitive electrochemical thrombin aptasensor using catalytic hairpin assembly (CHA) and bisferrocene was proposed for electrochemical beacon. Thrombin triggered the CHA reaction that in turn formed a number of double-stranded complexes,which are fixed on the surface of the gold electrode through potential-assisted Au−S deposition, and a large number of labeled bisferrocene are placed close to the gold electrode to generate electrochemical signal. The linear range of the electrochemical sensor was 0.25 pM-2.5 nM for thrombin with detection limit of 0.18 pM. This sensor can be employed to monitor the thrombin in human serum samples." @default.
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- W3111821971 date "2021-02-04" @default.
- W3111821971 modified "2023-10-14" @default.
- W3111821971 title "Enzyme‐free Recycling Amplification‐based Sensitive Electrochemical Thrombin Aptasensor" @default.
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- W3111821971 doi "https://doi.org/10.1002/elan.202060496" @default.
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