FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111842747> ?p ?o ?g. }

• W3111842747 endingPage "1416" @default.
• W3111842747 startingPage "1416" @default.
• W3111842747 abstract "Akhmeta virus is a zoonotic Orthopoxvirus first identified in 2013 in the country of Georgia. Subsequent ecological investigations in Georgia have found evidence that this virus is widespread in its geographic distribution within the country and in its host-range, with rodents likely involved in its circulation in the wild. Yet, little is known about the pathogenicity of this virus in rodents. We conducted the first laboratory infection of Akhmeta virus in CAST/EiJ Mus musculus to further characterize this novel virus. We found a dose-dependent effect on mortality and weight loss (p < 0.05). Anti-orthopoxvirus antibodies were detected in the second- and third-highest dose groups (5 × 104 pfu and 3 × 102 pfu) at euthanasia by day 10, and day 14 post-infection, respectively. Anti-orthopoxvirus antibodies were not detected in the highest dose group (3 × 106 pfu), which were euthanized at day 7 post-infection and had high viral load in tissues, suggesting they succumbed to disease prior to mounting an effective immune response. In order of highest burden, viable virus was detected in the nostril, lung, tail, liver and spleen. All individuals tested in the highest dose groups were DNAemic. Akhmeta virus was highly pathogenic in CAST/EiJ Mus musculus, causing 100% mortality when ≥3 × 102 pfu was administered." @default.
• W3111842747 created "2020-12-21" @default.
• W3111842747 creator A5003640752 @default.
• W3111842747 creator A5012453301 @default.
• W3111842747 creator A5012940734 @default.
• W3111842747 creator A5013528928 @default.
• W3111842747 creator A5016157129 @default.
• W3111842747 creator A5018261424 @default.
• W3111842747 creator A5025201501 @default.
• W3111842747 creator A5045826449 @default.
• W3111842747 creator A5053162775 @default.
• W3111842747 creator A5053281647 @default.
• W3111842747 creator A5063845759 @default.
• W3111842747 date "2020-12-09" @default.
• W3111842747 modified "2023-10-01" @default.
• W3111842747 title "Laboratory Infection of Novel Akhmeta Virus in CAST/EiJ Mice" @default.
• W3111842747 cites W1923059478 @default.
• W3111842747 cites W2009113474 @default.
• W3111842747 cites W2023119078 @default.
• W3111842747 cites W2026211433 @default.
• W3111842747 cites W2031312265 @default.
• W3111842747 cites W2046099321 @default.
• W3111842747 cites W2067628035 @default.
• W3111842747 cites W2067752514 @default.
• W3111842747 cites W2075170254 @default.
• W3111842747 cites W2083395893 @default.
• W3111842747 cites W2092192051 @default.
• W3111842747 cites W2093563486 @default.
• W3111842747 cites W2104384979 @default.
• W3111842747 cites W2113583982 @default.
• W3111842747 cites W2123281186 @default.
• W3111842747 cites W2141115692 @default.
• W3111842747 cites W2156004207 @default.
• W3111842747 cites W2172028732 @default.
• W3111842747 cites W2329892735 @default.
• W3111842747 cites W2404988603 @default.
• W3111842747 cites W2612412797 @default.
• W3111842747 cites W2768586468 @default.
• W3111842747 cites W2781979609 @default.
• W3111842747 cites W2973947555 @default.
• W3111842747 cites W2976622502 @default.
• W3111842747 cites W3011131469 @default.
• W3111842747 cites W3016738976 @default.
• W3111842747 doi "https://doi.org/10.3390/v12121416" @default.
• W3111842747 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7763702" @default.
• W3111842747 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33317132" @default.
• W3111842747 hasPublicationYear "2020" @default.
• W3111842747 type Work @default.
• W3111842747 sameAs 3111842747 @default.
• W3111842747 citedByCount "4" @default.
• W3111842747 countsByYear W31118427472022 @default.
• W3111842747 countsByYear W31118427472023 @default.
• W3111842747 crossrefType "journal-article" @default.
• W3111842747 hasAuthorship W3111842747A5003640752 @default.
• W3111842747 hasAuthorship W3111842747A5012453301 @default.
• W3111842747 hasAuthorship W3111842747A5012940734 @default.
• W3111842747 hasAuthorship W3111842747A5013528928 @default.
• W3111842747 hasAuthorship W3111842747A5016157129 @default.
• W3111842747 hasAuthorship W3111842747A5018261424 @default.
• W3111842747 hasAuthorship W3111842747A5025201501 @default.
• W3111842747 hasAuthorship W3111842747A5045826449 @default.
• W3111842747 hasAuthorship W3111842747A5053162775 @default.
• W3111842747 hasAuthorship W3111842747A5053281647 @default.
• W3111842747 hasAuthorship W3111842747A5063845759 @default.
• W3111842747 hasBestOaLocation W31118427471 @default.
• W3111842747 hasConcept C104317684 @default.
• W3111842747 hasConcept C159047783 @default.
• W3111842747 hasConcept C159654299 @default.
• W3111842747 hasConcept C203014093 @default.
• W3111842747 hasConcept C2522874641 @default.
• W3111842747 hasConcept C2779094796 @default.
• W3111842747 hasConcept C2780931953 @default.
• W3111842747 hasConcept C2781356689 @default.
• W3111842747 hasConcept C40767141 @default.
• W3111842747 hasConcept C54355233 @default.
• W3111842747 hasConcept C86803240 @default.
• W3111842747 hasConcept C8891405 @default.
• W3111842747 hasConceptScore W3111842747C104317684 @default.
• W3111842747 hasConceptScore W3111842747C159047783 @default.
• W3111842747 hasConceptScore W3111842747C159654299 @default.
• W3111842747 hasConceptScore W3111842747C203014093 @default.
• W3111842747 hasConceptScore W3111842747C2522874641 @default.
• W3111842747 hasConceptScore W3111842747C2779094796 @default.
• W3111842747 hasConceptScore W3111842747C2780931953 @default.
• W3111842747 hasConceptScore W3111842747C2781356689 @default.
• W3111842747 hasConceptScore W3111842747C40767141 @default.
• W3111842747 hasConceptScore W3111842747C54355233 @default.
• W3111842747 hasConceptScore W3111842747C86803240 @default.
• W3111842747 hasConceptScore W3111842747C8891405 @default.
• W3111842747 hasIssue "12" @default.
• W3111842747 hasLocation W31118427471 @default.
• W3111842747 hasLocation W31118427472 @default.
• W3111842747 hasLocation W31118427473 @default.
• W3111842747 hasLocation W31118427474 @default.
• W3111842747 hasOpenAccess W3111842747 @default.
• W3111842747 hasPrimaryLocation W31118427471 @default.
• W3111842747 hasRelatedWork W1481385684 @default.
• W3111842747 hasRelatedWork W1598935837 @default.

• next