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- W3111909837 abstract "Despite recent advances, current IPF therapies fail to halt progression and have limited impact on QoL. Hospitalization due to IPF is common. We studied real-world burden of IPF on QoL (EQ-5D), hospitalization, work impairment and healthcare visits. A large cross-sectional survey was conducted in France, Germany, Japan and the USA; 244 physicians reported data on 1,249 patients with IPF, 739 of whom provided self-reported data. EQ-5D health utility values in IPF were worse than moderate-to-severe chronic obstructive pulmonary disease and similar to non-small cell lung cancer, based on comparative real-world data. Those on treatment (84.7%) consulted a healthcare professional more than those untreated (8.5 vs 5.2 visits/year); 33% and 10% made ≥10 visits/year, respectively, largely for routine check-ups and repeat prescriptions. Hospitalization was more common when disease was perceived as severe by physicians, but 5–17% of patients with mild functional impairment were still hospitalized in the last year. Work productivity was impaired by 28%, 45%, 40% and 34% in France, Germany, Japan and USA, respectively. Data show the marked burden of IPF on QoL, work productivity and healthcare resource use, highlighting the need for optimization of current management. ACKNOWLEDGMENTS : This study was funded by Galapagos NV (Mechelen, Belgium). Writing support from Hannah Mace MPharmacol, CMPP (Aspire Scientific Ltd, Bollington, UK) was funded by Galapagos NV." @default.
- W3111909837 created "2020-12-21" @default.
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- W3111909837 date "2020-12-01" @default.
- W3111909837 modified "2023-10-14" @default.
- W3111909837 title "PRS78 Burden of Idiopathic Pulmonary Fibrosis (IPF) on Quality of Life (QOL), Work Productivity and Healthcare Use" @default.
- W3111909837 doi "https://doi.org/10.1016/j.jval.2020.08.1958" @default.
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