Matches in SemOpenAlex for { <https://semopenalex.org/work/W3111957505> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W3111957505 endingPage "1519" @default.
- W3111957505 startingPage "1519" @default.
- W3111957505 abstract "1519 Purpose: 1) to investigate the metabolic activity of the psoriatic skin lesions with FDG-PET/CT imaging and 2) to correlate FDG-PET findings with Psoriasis Area and Severity Index (PASI) scores, the most widely-used grading system for psoriasis. Methods: A subset of 33 subjects from a single center from a prospective multi-center clinical trial [NCT01553058] with moderate-to-severe psoriasis were included. Patients underwent whole-body FDG-PET/CT imaging 120 min after intravenous FDG. Each patient was graded by our ‘PET-PASI’ scoring system, a qualitative review of multi-plane reconstructions for both attenuation corrected (AC) and non-attenuation corrected (NAC) PET images. Each patients’ body was divided into four areas (head, arms, trunk, legs) and body involvement was scored from 0 (no involvement) to 6 (maximal involvement) corresponding to the percent of affected skin. The FDG uptake score was multiplied by body involvement and a scaling factor for the respective region (0.1 for head, 0.2 for arms, 0.3 for trunk 0.4 for legs), yielding the PET-PASI score. PASI and PET-PASI scores were correlated using Spearman’s rho analysis. Results: Our study demonstrated a moderate but statistically significant positive correlation between each patient’s corresponding PET-PASI and PASI scores (r=0.53, p<0.001). We also found positive correlations between PASI and PET-PASI component scores in four body regions (head and neck: r=0.22, trunk: r=0.48, upper limbs: r=0.26 and lower limbs: r=0.58). Conclusions: NAC images are easier to detect lesions such as superficial lymphoma and melanoma compared to AC scans. As such, AC and NAC FDG-PET/CT images may be utilized to evaluate lesions in patients with moderate-to-severe psoriasis. Our methodology could have future implications in diagnosis and therapeutic management of psoriasis." @default.
- W3111957505 created "2020-12-21" @default.
- W3111957505 creator A5013835650 @default.
- W3111957505 creator A5018682122 @default.
- W3111957505 creator A5036786265 @default.
- W3111957505 creator A5039751986 @default.
- W3111957505 creator A5047659019 @default.
- W3111957505 creator A5077662409 @default.
- W3111957505 creator A5081944301 @default.
- W3111957505 creator A5087410376 @default.
- W3111957505 creator A5088003622 @default.
- W3111957505 creator A5091298477 @default.
- W3111957505 date "2020-05-01" @default.
- W3111957505 modified "2023-09-23" @default.
- W3111957505 title "PET-PASI score: Utility of FDG-PET/CT in Psoriasis" @default.
- W3111957505 hasPublicationYear "2020" @default.
- W3111957505 type Work @default.
- W3111957505 sameAs 3111957505 @default.
- W3111957505 citedByCount "0" @default.
- W3111957505 crossrefType "journal-article" @default.
- W3111957505 hasAuthorship W3111957505A5013835650 @default.
- W3111957505 hasAuthorship W3111957505A5018682122 @default.
- W3111957505 hasAuthorship W3111957505A5036786265 @default.
- W3111957505 hasAuthorship W3111957505A5039751986 @default.
- W3111957505 hasAuthorship W3111957505A5047659019 @default.
- W3111957505 hasAuthorship W3111957505A5077662409 @default.
- W3111957505 hasAuthorship W3111957505A5081944301 @default.
- W3111957505 hasAuthorship W3111957505A5087410376 @default.
- W3111957505 hasAuthorship W3111957505A5088003622 @default.
- W3111957505 hasAuthorship W3111957505A5091298477 @default.
- W3111957505 hasConcept C123688308 @default.
- W3111957505 hasConcept C141071460 @default.
- W3111957505 hasConcept C16005928 @default.
- W3111957505 hasConcept C18903297 @default.
- W3111957505 hasConcept C2775842073 @default.
- W3111957505 hasConcept C2777011040 @default.
- W3111957505 hasConcept C2780564577 @default.
- W3111957505 hasConcept C2781197403 @default.
- W3111957505 hasConcept C2989005 @default.
- W3111957505 hasConcept C3018411727 @default.
- W3111957505 hasConcept C71924100 @default.
- W3111957505 hasConcept C86803240 @default.
- W3111957505 hasConceptScore W3111957505C123688308 @default.
- W3111957505 hasConceptScore W3111957505C141071460 @default.
- W3111957505 hasConceptScore W3111957505C16005928 @default.
- W3111957505 hasConceptScore W3111957505C18903297 @default.
- W3111957505 hasConceptScore W3111957505C2775842073 @default.
- W3111957505 hasConceptScore W3111957505C2777011040 @default.
- W3111957505 hasConceptScore W3111957505C2780564577 @default.
- W3111957505 hasConceptScore W3111957505C2781197403 @default.
- W3111957505 hasConceptScore W3111957505C2989005 @default.
- W3111957505 hasConceptScore W3111957505C3018411727 @default.
- W3111957505 hasConceptScore W3111957505C71924100 @default.
- W3111957505 hasConceptScore W3111957505C86803240 @default.
- W3111957505 hasOpenAccess W3111957505 @default.
- W3111957505 hasRelatedWork W1731713706 @default.
- W3111957505 hasRelatedWork W1938505580 @default.
- W3111957505 hasRelatedWork W2005134059 @default.
- W3111957505 hasRelatedWork W2098385765 @default.
- W3111957505 hasRelatedWork W2114330530 @default.
- W3111957505 hasRelatedWork W2280010419 @default.
- W3111957505 hasRelatedWork W2326535020 @default.
- W3111957505 hasRelatedWork W2529170031 @default.
- W3111957505 hasRelatedWork W2547828370 @default.
- W3111957505 hasRelatedWork W2553314579 @default.
- W3111957505 hasRelatedWork W2766773009 @default.
- W3111957505 hasRelatedWork W2797494384 @default.
- W3111957505 hasRelatedWork W2804065930 @default.
- W3111957505 hasRelatedWork W2909268534 @default.
- W3111957505 hasRelatedWork W2949060792 @default.
- W3111957505 hasRelatedWork W2949767084 @default.
- W3111957505 hasRelatedWork W2969906537 @default.
- W3111957505 hasRelatedWork W3107605218 @default.
- W3111957505 hasRelatedWork W3150097909 @default.
- W3111957505 hasRelatedWork W3212953565 @default.
- W3111957505 hasVolume "61" @default.
- W3111957505 isParatext "false" @default.
- W3111957505 isRetracted "false" @default.
- W3111957505 magId "3111957505" @default.
- W3111957505 workType "article" @default.