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- W3112139665 endingPage "91" @default.
- W3112139665 startingPage "76" @default.
- W3112139665 abstract "Vitiligo is a relatively common acquired pigmentation disorder that can cause significant psychological stress and stigmatism.This article aims to familiarize physicians with the clinical manifestations, evaluation, diagnosis, and management of vitiligo.A Pubmed search was conducted in Clinical Queries using the key term vitiligo. The search included meta-analyses, randomized controlled trials, clinical trials, observational studies, and reviews. The search was restricted to English language. The information retrieved from the above search was used in the compilation of the present article.Approximately one quarter of patients with vitiligo have the onset before 10 years of age. Genetic, immunological, neurogenic and environmental factors may have a role to play in the pathogenesis. Vitiligo typically presents as acquired depigmented, well-demarcated macules/patches that appear milk- or chalk-white in color. Lesions tend to increase in number and enlarge centrifugally in size with time. Sites of predilection include the face, followed by the neck, lower limbs, trunk, and upper limbs. The clinical course is generally unpredictable. In children with fair skin, no active treatment is usually necessary other than the use of sunscreens and camouflage cosmetics. If treatment is preferred for cosmesis, topical corticosteroids, topical calcineurin inhibitors, and narrowband ultraviolet B phototherapy are the mainstays of treatment.The therapeutic effect of all the treatment modalities varies considerably from individual to individual. As such, treatment must be individualized. In general, the best treatment response is seen in younger patients, recent disease onset, darker skin types, and head and neck lesions. Topical corticosteroids and calcineurin inhibitors are the treatment choice for those with localized disease. Topical calcineurin inhibitors are generally preferred for lesions on genitalia, intertriginous areas, face, and neck. Narrowband ultraviolet B phototherapy should be considered in patients who have widespread vitiligo or those with localized vitiligo associated with a significant impact on the quality of life who do not respond to treatment with topical corticosteroids and calcineurin inhibitors." @default.
- W3112139665 created "2020-12-21" @default.
- W3112139665 creator A5003762584 @default.
- W3112139665 creator A5027721931 @default.
- W3112139665 creator A5041887229 @default.
- W3112139665 creator A5065329974 @default.
- W3112139665 date "2021-05-01" @default.
- W3112139665 modified "2023-09-23" @default.
- W3112139665 title "Vitiligo: An Updated Narrative Review" @default.
- W3112139665 cites W1269454723 @default.
- W3112139665 cites W1494514268 @default.
- W3112139665 cites W1537893855 @default.
- W3112139665 cites W1558883997 @default.
- W3112139665 cites W177082782 @default.
- W3112139665 cites W1816954639 @default.
- W3112139665 cites W1841324455 @default.
- W3112139665 cites W1904850091 @default.
- W3112139665 cites W1919498774 @default.
- W3112139665 cites W1933351899 @default.
- W3112139665 cites W1938275350 @default.
- W3112139665 cites W1938420063 @default.
- W3112139665 cites W1953869513 @default.
- W3112139665 cites W1967187858 @default.
- W3112139665 cites W1984006272 @default.
- W3112139665 cites W1997141916 @default.
- W3112139665 cites W2003025495 @default.
- W3112139665 cites W2004832405 @default.
- W3112139665 cites W2014839119 @default.
- W3112139665 cites W2015336554 @default.
- W3112139665 cites W2018240927 @default.
- W3112139665 cites W2024047046 @default.
- W3112139665 cites W2024310737 @default.
- W3112139665 cites W2029113403 @default.
- W3112139665 cites W2052348403 @default.
- W3112139665 cites W2055539585 @default.
- W3112139665 cites W2076576722 @default.
- W3112139665 cites W2077273727 @default.
- W3112139665 cites W2081526651 @default.
- W3112139665 cites W2081889479 @default.
- W3112139665 cites W2084939108 @default.
- W3112139665 cites W2086106591 @default.
- W3112139665 cites W2094081716 @default.
- W3112139665 cites W2096898586 @default.
- W3112139665 cites W2098417701 @default.
- W3112139665 cites W2098494405 @default.
- W3112139665 cites W2101476612 @default.
- W3112139665 cites W2101577055 @default.
- W3112139665 cites W2104690458 @default.
- W3112139665 cites W2122497850 @default.
- W3112139665 cites W2130326596 @default.
- W3112139665 cites W2137650680 @default.
- W3112139665 cites W2154667430 @default.
- W3112139665 cites W2158880998 @default.
- W3112139665 cites W2161497313 @default.
- W3112139665 cites W2176908675 @default.
- W3112139665 cites W2220354412 @default.
- W3112139665 cites W2237788291 @default.
- W3112139665 cites W2401445293 @default.
- W3112139665 cites W2414422683 @default.
- W3112139665 cites W2473757338 @default.
- W3112139665 cites W2510052370 @default.
- W3112139665 cites W2512345040 @default.
- W3112139665 cites W2527192536 @default.
- W3112139665 cites W2535961187 @default.
- W3112139665 cites W2574693936 @default.
- W3112139665 cites W2595511842 @default.
- W3112139665 cites W2596110276 @default.
- W3112139665 cites W2596158018 @default.
- W3112139665 cites W2596339367 @default.
- W3112139665 cites W2596691239 @default.
- W3112139665 cites W2597318195 @default.
- W3112139665 cites W2603241315 @default.
- W3112139665 cites W2608870338 @default.
- W3112139665 cites W2615516063 @default.
- W3112139665 cites W2620993338 @default.
- W3112139665 cites W2626089303 @default.
- W3112139665 cites W2626458389 @default.
- W3112139665 cites W2742061521 @default.
- W3112139665 cites W2752689652 @default.
- W3112139665 cites W2760313272 @default.
- W3112139665 cites W2762693917 @default.
- W3112139665 cites W2763238453 @default.
- W3112139665 cites W2766234204 @default.
- W3112139665 cites W2773249491 @default.
- W3112139665 cites W2779634146 @default.
- W3112139665 cites W2785741518 @default.
- W3112139665 cites W2786211708 @default.
- W3112139665 cites W2787739631 @default.
- W3112139665 cites W2790598547 @default.
- W3112139665 cites W2793368470 @default.
- W3112139665 cites W2800029095 @default.
- W3112139665 cites W2801142924 @default.
- W3112139665 cites W2804701386 @default.
- W3112139665 cites W2806449127 @default.
- W3112139665 cites W2826674193 @default.
- W3112139665 cites W2883927341 @default.
- W3112139665 cites W2885312066 @default.
- W3112139665 cites W2885976193 @default.