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- W3112298052 endingPage "32631" @default.
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- W3112298052 abstract "Microbial infections originating from medical care facilities are raising serious concerns across the globe. Therefore, nanotechnology-derived nanostructures have been investigated and explored due to their promising characteristics. In view of this, silver-based antimicrobial hydrogels as an alternative to antibiotic-based creams could play a crucial role in combating such infections. Toward this goal, we report a simple method for the synthesis and assembly of silver nanoparticles in a biopolymer physical gel derived from Abroma augusta plant in imparting antimicrobial properties against nosocomial pathogens. Synthesized silver nanoparticles (diameter, 30 ± 10 nm) were uniformly distributed inside the hydrogel. Such synthesized hydrogel assembly of silver nanoparticles dispersed in the biopolymer matrix exhibited hemocompatibility and antimicrobial and antibiofilm characteristics against nosocomial pathogens. The developed hydrogel as a surface coating offers reduced hardness and modulus value, thereby minimizing the brittleness tendency of the gel in the dried state. Hence, we believe that the hierarchical assembly of our hydrogel owing to its functional activity, host toxicity, and stability could possibly be used as an antimicrobial ointment for bacterial infection control." @default.
- W3112298052 created "2020-12-21" @default.
- W3112298052 creator A5011172642 @default.
- W3112298052 creator A5045345623 @default.
- W3112298052 creator A5063909855 @default.
- W3112298052 creator A5065378618 @default.
- W3112298052 date "2020-12-09" @default.
- W3112298052 modified "2023-10-12" @default.
- W3112298052 title "Hierarchical Assembly of Nanodimensional Silver–Silver Oxide Physical Gels Controlling Nosocomial Infections" @default.
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