Matches in SemOpenAlex for { <https://semopenalex.org/work/W3112404417> ?p ?o ?g. }
- W3112404417 endingPage "113084" @default.
- W3112404417 startingPage "113084" @default.
- W3112404417 abstract "Atovaquone belongs to a naphthoquinone class of drugs and is used in combination with proguanil (Malarone) for the treatment of acute, uncomplicated malaria caused by Plasmodium falciparum (including chloroquine-resistant P. falciparum/P. vivax). Numerous quinone-derived compounds have attracted considerable attention in the last few decades due to their potential in antimalarial drug discovery. Several semi-synthetic derivatives of natural quinones, synthetic quinones (naphtho-/benzo-quinone, anthraquinones, thiazinoquinones), and quinone-based hybrids were explored for their in vitro and in vivo antimalarial activities. A careful literature survey revealed that this topic has not been compiled as a review article so far. Therefore, we herein summarise the recent discovery (the year 2009–2020) of quinone based antimalarial compounds in chronological order. This compilation would be very useful towards the exploration of novel quinone-derived compounds against malarial parasites with promising efficacy and lesser side effects." @default.
- W3112404417 created "2020-12-21" @default.
- W3112404417 creator A5004762735 @default.
- W3112404417 creator A5019008348 @default.
- W3112404417 creator A5039878184 @default.
- W3112404417 date "2021-01-01" @default.
- W3112404417 modified "2023-09-30" @default.
- W3112404417 title "Antimalarial application of quinones: A recent update" @default.
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