Matches in SemOpenAlex for { <https://semopenalex.org/work/W3112728374> ?p ?o ?g. }
- W3112728374 endingPage "1236" @default.
- W3112728374 startingPage "1236" @default.
- W3112728374 abstract "The blood-brain barrier (BBB), which is composed of endothelial cells, pericytes, astrocytes, and neurons, separates the brain extracellular fluid from the circulating blood, and maintains the homeostasis of the central nervous system (CNS). The BBB endothelial cells have well-developed tight junctions (TJs) and express specific polarized transport systems to tightly control the paracellular movements of solutes, ions, and water. There are two types of TJs: bicellular TJs (bTJs), which is a structure at the contact of two cells, and tricellular TJs (tTJs), which is a structure at the contact of three cells. Claudin-5 and angulin-1 are important components of bTJs and tTJs in the brain, respectively. Here, we review TJ-modulating bioprobes that enable drug delivery to the brain across the BBB, focusing on claudin-5 and angulin-1." @default.
- W3112728374 created "2020-12-21" @default.
- W3112728374 creator A5027002340 @default.
- W3112728374 creator A5042908076 @default.
- W3112728374 creator A5045714002 @default.
- W3112728374 creator A5054512353 @default.
- W3112728374 creator A5086288542 @default.
- W3112728374 creator A5090688807 @default.
- W3112728374 date "2020-12-19" @default.
- W3112728374 modified "2023-10-17" @default.
- W3112728374 title "Tight Junction Modulating Bioprobes for Drug Delivery System to the Brain: A Review" @default.
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