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• W3112815326 abstract "Interstitial lung diseases (ILDs) including those associated with systemic sclerosis (SSc) are a heterogeneous group of disorders. ILD can also develop a progressive fibrosing (PF) phenotype similar to that observed in idiopathic pulmonary fibrosis (IPF). The of this study were to describe patients’ characteristics, healthcare resource consumptions and costs of PF-ILD and SSc-ILD in a real-world setting in France. The French administrative healthcare database (Système national des données de santé, SNDS) was used to describe PF-ILD and SSc-ILD patients’ characteristics and healthcare costs between January 2010 and December 2017. PF-ILD and SSc-ILD patients were identified through a combination of different algorithms within the SNDS using ICD codes. Patients’ characteristics, healthcare resource use and associated costs were extracted from the database and analysed. A multivariate analysis using a Cox proportional hazard model is currently ongoing to estimate predictive factors associated with increased costs and will be described. 14,413 PF-ILD patients and 3,333 SSc-ILD patients were identified. 48.1% of PF-ILD patients and 75.6% of SSc-ILD patients were female. Mean age (± standard deviation) was 68.4 ± 15.0 years and 60.6 ±14.4 years for PF-ILD and SSc-ILD patients, respectively. Mean annual healthcare costs per patient were €81,286 for PF-ILD and €25,753 for SSc-ILD, mostly attributable to hospitalizations (respectively, 67% and 84% of mean total annual healthcare costs). Palliative care represented 27% of the mean total annual healthcare costs per PF-ILD patient. Mean annual drug costs per patient were €456 and €883 for PF-ILD and SSc-ILD, respectively. The results underline the high economic burden from caring of PF-ILD and SSc-ILD in a real-life setting in France. Specifically, mean annual healthcare costs per SSc-ILD and PF-ILD patient were mainly driven by frequent hospitalizations, with significant palliative care cost for PF-ILD patients." @default.
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• W3112815326 date "2020-12-01" @default.
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• W3112815326 title "PRS11 Healthcare Resource Utilization and Associated Costs of Progressive Fibrosing Interstitial LUNG Disease (PF-ILD) and Systemic Sclerosis Associated Interstitial LUNG Disease (SSC-ILD) in France." @default.
• W3112815326 doi "https://doi.org/10.1016/j.jval.2020.08.1891" @default.
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