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• W3113014044 abstract "The aim of this study is to focus attention on obstructive sleep apnoea hypopnoea syndrome (OSHAS) as a sequela of non-surgical treatments of selected head and neck cancer (HNca), sharing our experience in drug-induced sleep endoscopy (DISE). To the best of our knowledge, this is the first study that documents dynamic anatomical and functional alterations during sleep in irradiated OSAHS patients by DISE.A retrospective study of patients affected by OSAHS referring to our department from January 2018 to December 2019 was carried out. Inclusion criteria were: patients who underwent radiation or chemo-radiation for HNca affecting upper airways that presented sleep-related breathing disorders after treatment.6 patients with moderate to severe OSAHS and a clinical story of previous non-surgical treatment for an HNca were enrolled. DISE showed in all patients typical anatomical alterations observed in irradiated individuals. Four patients were treated with continuous positive airway pressure, while 2 subjects were treated with tailored minimal invasive surgery without post-operative complications.Our results suggest that minimal invasive surgical treatments can be a good therapeutic option in very selected patients with post-irradiation iatrogenic OSAHS.Apnee ostruttive del sonno dopo radioterapia per tumori del testa-collo.Lo scopo di questo studio retrospettivo è focalizzare l’attenzione sull’OSAS come sequela di trattamenti non chirurgici per tumori del distretto testa-collo (HNca), condividendo la nostra esperienza con la “drug induced sleep endoscopy” (DISE) e la nostra casistica. Per quanto ne sappiamo, questo è il primo studio che documenta alterazioni anatomiche e funzionali dinamiche mediante DISE in pazienti irradiati che hanno sviluppato OSAS.È stato condotto uno studio retrospettivo su pazienti affetti da OSAS afferenti alla nostra struttura da gennaio 2018 a dicembre 2019. Sono stati inclusi nello studio pazienti con anamnesi positiva per trattamento non chirurgico di HNca che hanno sviluppato OSAS dopo il trattamento.Sono stati arruolati 6 pazienti con OSAS da moderata a grave con una storia clinica di precedente trattamento non chirurgico per un HNca. La DISE ha mostrato in tutti i nostri pazienti tipiche alterazioni anatomiche osservate pazienti irradiati. 4 pazienti sono stati trattati con CPAP mentre 2 soggetti sono stati sottoposti a chirurgia mininvasiva senza complicazioni post-operatorie.I nostri risultati suggeriscono che i trattamenti chirurgici mini invasivi possono essere una buona opzione terapeutica in pazienti con OSAS iatrogena post-radioterapia ben selezionati." @default.
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• W3113014044 date "2020-10-01" @default.
• W3113014044 modified "2023-09-24" @default.
• W3113014044 title "Obstructive sleep apnoea after radiotherapy for head and neck cancer" @default.
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• W3113014044 doi "https://doi.org/10.14639/0392-100x-n0895" @default.
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