FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113098651> ?p ?o ?g. }

• W3113098651 abstract "Abstract Background Lysine acylations are important post-translational modifications that are present in both eukaryotes and prokaryotes, regulating diverse cellular functions. Our knowledge of the microbiome lysine acylation remains limited due to the lack of efficient analytical and bioinformatics methods for complex microbial communities. Results We show that serial enrichment using motif antibodies successfully captures peptides containing lysine acetylation, propionylation and succinylation from human gut microbiome samples. A new bioinformatic workflow consisting of unrestricted database search confidently identified >60,000 acetylated, and ~20,000 propionylated and succinylated gut microbial peptides. Characterization of these identified modification-specific metaproteomes, i.e. meta-PTMomes, demonstrates that lysine acylations are differentially distributed in microbial species with different metabolic capabilities. Conclusion This study provides an analytical framework, consisting of a serial immunoaffinity enrichment and an open database search strategy, for the study of lysine acylations in microbiome, which enables functional microbiome studies at the post-translational level." @default.
• W3113098651 created "2020-12-21" @default.
• W3113098651 creator A5000390476 @default.
• W3113098651 creator A5002186564 @default.
• W3113098651 creator A5002417397 @default.
• W3113098651 creator A5008522740 @default.
• W3113098651 creator A5036255722 @default.
• W3113098651 creator A5051417425 @default.
• W3113098651 creator A5051554394 @default.
• W3113098651 creator A5054261613 @default.
• W3113098651 creator A5063707093 @default.
• W3113098651 date "2020-12-14" @default.
• W3113098651 modified "2023-09-27" @default.
• W3113098651 title "Exploring the microbiome-wide lysine acetylation, succinylation and propionylation in human gut microbiota" @default.
• W3113098651 cites W1480858518 @default.
• W3113098651 cites W1967619674 @default.
• W3113098651 cites W1974515407 @default.
• W3113098651 cites W1993548347 @default.
• W3113098651 cites W2013955377 @default.
• W3113098651 cites W2036321220 @default.
• W3113098651 cites W2045204781 @default.
• W3113098651 cites W2059651000 @default.
• W3113098651 cites W2114836779 @default.
• W3113098651 cites W2161185495 @default.
• W3113098651 cites W2274927794 @default.
• W3113098651 cites W2324909991 @default.
• W3113098651 cites W2511763764 @default.
• W3113098651 cites W2607310450 @default.
• W3113098651 cites W2734871402 @default.
• W3113098651 cites W2765314233 @default.
• W3113098651 cites W2766183905 @default.
• W3113098651 cites W2766903152 @default.
• W3113098651 cites W2773610445 @default.
• W3113098651 cites W2792021903 @default.
• W3113098651 cites W2808973977 @default.
• W3113098651 cites W2894727674 @default.
• W3113098651 cites W2899760200 @default.
• W3113098651 cites W2911442568 @default.
• W3113098651 cites W2951517287 @default.
• W3113098651 cites W2981643974 @default.
• W3113098651 cites W2993476941 @default.
• W3113098651 cites W3024422389 @default.
• W3113098651 cites W3034548692 @default.
• W3113098651 cites W3049003747 @default.
• W3113098651 doi "https://doi.org/10.1101/2020.12.14.422746" @default.
• W3113098651 hasPublicationYear "2020" @default.
• W3113098651 type Work @default.
• W3113098651 sameAs 3113098651 @default.
• W3113098651 citedByCount "0" @default.
• W3113098651 crossrefType "posted-content" @default.
• W3113098651 hasAuthorship W3113098651A5000390476 @default.
• W3113098651 hasAuthorship W3113098651A5002186564 @default.
• W3113098651 hasAuthorship W3113098651A5002417397 @default.
• W3113098651 hasAuthorship W3113098651A5008522740 @default.
• W3113098651 hasAuthorship W3113098651A5036255722 @default.
• W3113098651 hasAuthorship W3113098651A5051417425 @default.
• W3113098651 hasAuthorship W3113098651A5051554394 @default.
• W3113098651 hasAuthorship W3113098651A5054261613 @default.
• W3113098651 hasAuthorship W3113098651A5063707093 @default.
• W3113098651 hasBestOaLocation W31130986511 @default.
• W3113098651 hasConcept C104317684 @default.
• W3113098651 hasConcept C119157956 @default.
• W3113098651 hasConcept C12290205 @default.
• W3113098651 hasConcept C143121216 @default.
• W3113098651 hasConcept C185592680 @default.
• W3113098651 hasConcept C190944805 @default.
• W3113098651 hasConcept C2776016237 @default.
• W3113098651 hasConcept C2910274206 @default.
• W3113098651 hasConcept C3019978661 @default.
• W3113098651 hasConcept C515207424 @default.
• W3113098651 hasConcept C55493867 @default.
• W3113098651 hasConcept C60644358 @default.
• W3113098651 hasConcept C70721500 @default.
• W3113098651 hasConcept C86803240 @default.
• W3113098651 hasConcept C91478284 @default.
• W3113098651 hasConceptScore W3113098651C104317684 @default.
• W3113098651 hasConceptScore W3113098651C119157956 @default.
• W3113098651 hasConceptScore W3113098651C12290205 @default.
• W3113098651 hasConceptScore W3113098651C143121216 @default.
• W3113098651 hasConceptScore W3113098651C185592680 @default.
• W3113098651 hasConceptScore W3113098651C190944805 @default.
• W3113098651 hasConceptScore W3113098651C2776016237 @default.
• W3113098651 hasConceptScore W3113098651C2910274206 @default.
• W3113098651 hasConceptScore W3113098651C3019978661 @default.
• W3113098651 hasConceptScore W3113098651C515207424 @default.
• W3113098651 hasConceptScore W3113098651C55493867 @default.
• W3113098651 hasConceptScore W3113098651C60644358 @default.
• W3113098651 hasConceptScore W3113098651C70721500 @default.
• W3113098651 hasConceptScore W3113098651C86803240 @default.
• W3113098651 hasConceptScore W3113098651C91478284 @default.
• W3113098651 hasLocation W31130986511 @default.
• W3113098651 hasLocation W31130986512 @default.
• W3113098651 hasOpenAccess W3113098651 @default.
• W3113098651 hasPrimaryLocation W31130986511 @default.
• W3113098651 hasRelatedWork W1984658022 @default.
• W3113098651 hasRelatedWork W2014390271 @default.
• W3113098651 hasRelatedWork W2028662668 @default.
• W3113098651 hasRelatedWork W2194211099 @default.
• W3113098651 hasRelatedWork W2863773080 @default.
• W3113098651 hasRelatedWork W2890475088 @default.

• next