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- W3113142786 abstract "FeochromocytĂłm (FEO) a paragangliĂłm (PGL) sĂş zriedkavĂŠ katecholamĂny produkujĂşce neuroendokrinnĂŠ tumory vychĂĄdzajĂşce z drene nadobliÄky alebo z extraadrenĂĄlnych sympatikovĂ˝ch a parasympatikovĂ˝ch gangliĂ. Vo väÄĹĄine prĂpadov FEO/PGL ide o benĂgne tumory, avĹĄak metastatickĂŠ ochorenie nie je vĂ˝nimkou, predovĹĄetkĂ˝m u pacientov so ĹĄpecifickĂ˝m genetickĂ˝m pozadĂm. Aj keÄ FEO/PGL boli popĂsanĂŠ uĹž pred viac ako storoÄĂm, diagnostika a lieÄba metastatickĂŠho ochorenia sĂş stĂĄle problematickĂŠ. Pokrok v porozumenĂ molekulĂĄrnym a metabolickĂ˝m zmenĂĄm asociovanĂ˝m s tumorigenĂŠzou nĂĄs vedie bliŞťie k identifikĂĄcii podstaty tĂ˝chto tumorov. NovĂŠ poznatky umoĹžnili vyvinúż presnejĹĄie diagnostickĂŠ metĂłdy a identifikovaĹĽ molekulĂĄrne terapeutickĂŠ ciele, ktorĂŠ by mali prispieĹĽ k zlepĹĄeniu starostlivosti o pacientov s metastatickĂ˝m FEO/PGL." @default.
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- W3113142786 date "2017-09-01" @default.
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- W3113142786 title "Diagnosis and management of metastatic pheochromocytoma and paraganglioma" @default.
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- W3113142786 doi "https://doi.org/10.36290/vnl.2017.116" @default.
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