FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113164019> ?p ?o ?g. }

• W3113164019 abstract "Abstract Multiple recent studies have shown that motor activity greatly impacts the activity of primary sensory areas like V1. Yet, the role of this motor related activity in sensory processing is still unclear. Here we dissect how these behavior signals are broadcast to different layers and areas of the visual cortex. To do so, we leveraged a standardized and spontaneous behavioral fidget event in passively viewing mice. Importantly, this behavior event had no relevance to any ongoing task allowing us to compare its neuronal correlate with visually relevant behavior like running. A large two-photon Ca 2+ imaging database of neuronal responses uncovered four neural response types during fidgets that were surprisingly consistent in their proportion and response patterns across all visual areas and layers of the visual cortex. Indeed, the layer and area identity could not be decoded above chance level based only on neuronal recordings. In contrast to running behavior, fidget evoked neural responses were independent to visual processing. The broad availability of visually orthogonal standardized behavior signals could be a key component in how the cortex selects, learns and binds local sensory information with motor outputs. Contrary to relevant motor outputs, irrelevant motor signals would use a separate neural subspaces. Significance Statement Recent studies have shown contextual and behavioral variables to dominate brain-wide activity, but yet it is unknown how this information is broadcast across cortical layers and areas. Using a large two-photon dataset collected in mice passively viewing a battery of visual stimuli, we characterized the neuronal response of neurons of the visual cortex to a standardized fidget behavior. We found that as much as 47% of excitatory neurons show significant co-activity with fidgets. Throughout all areas and layers we recorded from, those responses were distributed across surprisingly consistent three neural response types. Further analysis showed no interaction between fidget neural events and cells’ visual stimulus responses, contrasting with feedback neural signals induced by running. These contrasting response distribution patterns suggest that behavioral neuronal correlates are broadly available but will modulate sensory responses depending on their relevance to local sensory inputs." @default.
• W3113164019 created "2020-12-21" @default.
• W3113164019 creator A5001851740 @default.
• W3113164019 creator A5002571736 @default.
• W3113164019 creator A5016337396 @default.
• W3113164019 creator A5016930737 @default.
• W3113164019 creator A5017247012 @default.
• W3113164019 creator A5026106102 @default.
• W3113164019 creator A5030420322 @default.
• W3113164019 creator A5032124807 @default.
• W3113164019 creator A5034682334 @default.
• W3113164019 creator A5035637769 @default.
• W3113164019 creator A5057900058 @default.
• W3113164019 creator A5066553704 @default.
• W3113164019 creator A5072386664 @default.
• W3113164019 creator A5089603918 @default.
• W3113164019 date "2020-12-16" @default.
• W3113164019 modified "2023-09-23" @default.
• W3113164019 title "A standardized behavioral event equally impacts the activity of cortical visual areas and layers" @default.
• W3113164019 cites W1930970642 @default.
• W3113164019 cites W1972869628 @default.
• W3113164019 cites W2002667643 @default.
• W3113164019 cites W2005725359 @default.
• W3113164019 cites W2016708835 @default.
• W3113164019 cites W2039881289 @default.
• W3113164019 cites W2040165511 @default.
• W3113164019 cites W2052625533 @default.
• W3113164019 cites W2068809501 @default.
• W3113164019 cites W2073319296 @default.
• W3113164019 cites W2075312701 @default.
• W3113164019 cites W2078340953 @default.
• W3113164019 cites W2552737632 @default.
• W3113164019 cites W2567050542 @default.
• W3113164019 cites W2767493192 @default.
• W3113164019 cites W2888545175 @default.
• W3113164019 cites W2889326414 @default.
• W3113164019 cites W2896255096 @default.
• W3113164019 cites W2937274403 @default.
• W3113164019 cites W2947039493 @default.
• W3113164019 cites W2952738901 @default.
• W3113164019 cites W2976024218 @default.
• W3113164019 cites W2982557070 @default.
• W3113164019 cites W2994737554 @default.
• W3113164019 cites W2997409530 @default.
• W3113164019 cites W3014953422 @default.
• W3113164019 cites W3016391357 @default.
• W3113164019 cites W3024792047 @default.
• W3113164019 doi "https://doi.org/10.1101/2020.12.15.422967" @default.
• W3113164019 hasPublicationYear "2020" @default.
• W3113164019 type Work @default.
• W3113164019 sameAs 3113164019 @default.
• W3113164019 citedByCount "1" @default.
• W3113164019 countsByYear W31131640192023 @default.
• W3113164019 crossrefType "posted-content" @default.
• W3113164019 hasAuthorship W3113164019A5001851740 @default.
• W3113164019 hasAuthorship W3113164019A5002571736 @default.
• W3113164019 hasAuthorship W3113164019A5016337396 @default.
• W3113164019 hasAuthorship W3113164019A5016930737 @default.
• W3113164019 hasAuthorship W3113164019A5017247012 @default.
• W3113164019 hasAuthorship W3113164019A5026106102 @default.
• W3113164019 hasAuthorship W3113164019A5030420322 @default.
• W3113164019 hasAuthorship W3113164019A5032124807 @default.
• W3113164019 hasAuthorship W3113164019A5034682334 @default.
• W3113164019 hasAuthorship W3113164019A5035637769 @default.
• W3113164019 hasAuthorship W3113164019A5057900058 @default.
• W3113164019 hasAuthorship W3113164019A5066553704 @default.
• W3113164019 hasAuthorship W3113164019A5072386664 @default.
• W3113164019 hasAuthorship W3113164019A5089603918 @default.
• W3113164019 hasBestOaLocation W31131640191 @default.
• W3113164019 hasConcept C142853389 @default.
• W3113164019 hasConcept C15744967 @default.
• W3113164019 hasConcept C169760540 @default.
• W3113164019 hasConcept C2779345533 @default.
• W3113164019 hasConcept C41008148 @default.
• W3113164019 hasConcept C542102704 @default.
• W3113164019 hasConcept C74254510 @default.
• W3113164019 hasConcept C94487597 @default.
• W3113164019 hasConceptScore W3113164019C142853389 @default.
• W3113164019 hasConceptScore W3113164019C15744967 @default.
• W3113164019 hasConceptScore W3113164019C169760540 @default.
• W3113164019 hasConceptScore W3113164019C2779345533 @default.
• W3113164019 hasConceptScore W3113164019C41008148 @default.
• W3113164019 hasConceptScore W3113164019C542102704 @default.
• W3113164019 hasConceptScore W3113164019C74254510 @default.
• W3113164019 hasConceptScore W3113164019C94487597 @default.
• W3113164019 hasLocation W31131640191 @default.
• W3113164019 hasOpenAccess W3113164019 @default.
• W3113164019 hasPrimaryLocation W31131640191 @default.
• W3113164019 hasRelatedWork W2010783874 @default.
• W3113164019 hasRelatedWork W2097743332 @default.
• W3113164019 hasRelatedWork W2148804598 @default.
• W3113164019 hasRelatedWork W2766387042 @default.
• W3113164019 hasRelatedWork W2883627903 @default.
• W3113164019 hasRelatedWork W2889054662 @default.
• W3113164019 hasRelatedWork W2951899425 @default.
• W3113164019 hasRelatedWork W3176877034 @default.
• W3113164019 hasRelatedWork W3193543236 @default.
• W3113164019 hasRelatedWork W3195491161 @default.
• W3113164019 isParatext "false" @default.
• W3113164019 isRetracted "false" @default.

• next