FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113186002> ?p ?o ?g. }

• W3113186002 abstract "<h3>Background</h3> Obesity and diabetes put patients are at higher risk of mortality and other adverse outcomes following coronary artery bypass grafting (CABG) and are becoming more common. The use of bilateral internal thoracic arteries (BITA) can potentially offer survival benefit in higher risk patients compared to single internal thoracic artery (SITA) in patients undergoing CABG. Current evidence does not support the routine use of BITA and this approach is associated with a higher risk of sternal wound complications. <h3>Methods</h3> We conducted a systematic review of the literature to identify observational studies and randomised controlled trials (RCT) comparing efficacy (mortality) and safety (sternal wound infection) of BITA and SITA in diabetic and obese patients. <h3>Results</h3> Eighteen observational studies and one RCT (subgroup analysis) were identified comparing BITA and SITA in 19,589 patients with diabetes. In contrast there were just two observational studies and one RCT (subgroup analysis) comparing BITA and SITA in 6972 obese patients. Pooled analysis demonstrated significant mortality benefit of BITA compared to SITA in diabetic patients (risk ratio [RR] 0.79; 95% confidence interval [CI] 0.70, 0.90; Z=3.62, p=0.0003; I2=88%) (Figure 1b). Pooled analysis in obese patients found no significant difference in mortality rates between BITA and SITA (RR 0.73, 95% CI 0.47, 1.12; Z=1.43, p=0.15; I2=78%), although the overall effect was for a beneficial trend for BITA (Figure 1a). A significantly higher rate of sternal wound complications following BITA was observed in diabetic (RR 1.53, 95% CI 1.23, 1.90; Z=3.86, p=0.0001; I2=4%) and obese patients (RR 2.24, 95% CI 1.63, 3.07; Z=5.00, p<0.00001; I2=0%). <h3>Conclusions</h3> In a pooled analysis, BITA is associated with better long-term survival in diabetic patients, but most of the supportive data comes from observational studies. The effects of BITA grafting in patients who are obese is uncertain due to low numbers of patients available for analysis. BITA is associated with higher rates of sternal wound complications than SITA in both diabetic and obese patients. Further studies are needed to understand the benefits and risks of multiple arterial grafting in patients with diabetes and/or obesity. <h3>Conflict of Interest</h3> None" @default.
• W3113186002 created "2020-12-21" @default.
• W3113186002 creator A5002030514 @default.
• W3113186002 creator A5018195873 @default.
• W3113186002 creator A5021710866 @default.
• W3113186002 creator A5027337947 @default.
• W3113186002 creator A5030079078 @default.
• W3113186002 creator A5030956368 @default.
• W3113186002 creator A5037858868 @default.
• W3113186002 creator A5053362604 @default.
• W3113186002 creator A5054566661 @default.
• W3113186002 creator A5070823804 @default.
• W3113186002 date "2020-07-01" @default.
• W3113186002 modified "2023-09-26" @default.
• W3113186002 title "123 Systematic review and meta-analysis comparing bilateral versus single internal thoracic artery grafts in patients with diabetes and obesity undergoing coronary artery bypass graft surgery" @default.
• W3113186002 doi "https://doi.org/10.1136/heartjnl-2020-bcs.123" @default.
• W3113186002 hasPublicationYear "2020" @default.
• W3113186002 type Work @default.
• W3113186002 sameAs 3113186002 @default.
• W3113186002 citedByCount "0" @default.
• W3113186002 crossrefType "proceedings-article" @default.
• W3113186002 hasAuthorship W3113186002A5002030514 @default.
• W3113186002 hasAuthorship W3113186002A5018195873 @default.
• W3113186002 hasAuthorship W3113186002A5021710866 @default.
• W3113186002 hasAuthorship W3113186002A5027337947 @default.
• W3113186002 hasAuthorship W3113186002A5030079078 @default.
• W3113186002 hasAuthorship W3113186002A5030956368 @default.
• W3113186002 hasAuthorship W3113186002A5037858868 @default.
• W3113186002 hasAuthorship W3113186002A5053362604 @default.
• W3113186002 hasAuthorship W3113186002A5054566661 @default.
• W3113186002 hasAuthorship W3113186002A5070823804 @default.
• W3113186002 hasBestOaLocation W31131860021 @default.
• W3113186002 hasConcept C126322002 @default.
• W3113186002 hasConcept C134018914 @default.
• W3113186002 hasConcept C141071460 @default.
• W3113186002 hasConcept C164705383 @default.
• W3113186002 hasConcept C168563851 @default.
• W3113186002 hasConcept C187960798 @default.
• W3113186002 hasConcept C23131810 @default.
• W3113186002 hasConcept C2775901492 @default.
• W3113186002 hasConcept C2776820930 @default.
• W3113186002 hasConcept C2779670087 @default.
• W3113186002 hasConcept C3017915907 @default.
• W3113186002 hasConcept C44249647 @default.
• W3113186002 hasConcept C555293320 @default.
• W3113186002 hasConcept C71924100 @default.
• W3113186002 hasConcept C82789193 @default.
• W3113186002 hasConcept C95190672 @default.
• W3113186002 hasConceptScore W3113186002C126322002 @default.
• W3113186002 hasConceptScore W3113186002C134018914 @default.
• W3113186002 hasConceptScore W3113186002C141071460 @default.
• W3113186002 hasConceptScore W3113186002C164705383 @default.
• W3113186002 hasConceptScore W3113186002C168563851 @default.
• W3113186002 hasConceptScore W3113186002C187960798 @default.
• W3113186002 hasConceptScore W3113186002C23131810 @default.
• W3113186002 hasConceptScore W3113186002C2775901492 @default.
• W3113186002 hasConceptScore W3113186002C2776820930 @default.
• W3113186002 hasConceptScore W3113186002C2779670087 @default.
• W3113186002 hasConceptScore W3113186002C3017915907 @default.
• W3113186002 hasConceptScore W3113186002C44249647 @default.
• W3113186002 hasConceptScore W3113186002C555293320 @default.
• W3113186002 hasConceptScore W3113186002C71924100 @default.
• W3113186002 hasConceptScore W3113186002C82789193 @default.
• W3113186002 hasConceptScore W3113186002C95190672 @default.
• W3113186002 hasLocation W31131860021 @default.
• W3113186002 hasOpenAccess W3113186002 @default.
• W3113186002 hasPrimaryLocation W31131860021 @default.
• W3113186002 hasRelatedWork W1526267197 @default.
• W3113186002 hasRelatedWork W2114346778 @default.
• W3113186002 hasRelatedWork W2210573147 @default.
• W3113186002 hasRelatedWork W2462299284 @default.
• W3113186002 hasRelatedWork W2508175216 @default.
• W3113186002 hasRelatedWork W2783180894 @default.
• W3113186002 hasRelatedWork W3109537979 @default.
• W3113186002 hasRelatedWork W3179274514 @default.
• W3113186002 hasRelatedWork W4212933565 @default.
• W3113186002 hasRelatedWork W4285593650 @default.
• W3113186002 isParatext "false" @default.
• W3113186002 isRetracted "false" @default.
• W3113186002 magId "3113186002" @default.
• W3113186002 workType "article" @default.