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• W3113209092 abstract "ABSTRACT Rationale The increasing incidence of extreme wildfire is becoming a concern for public health. Although long-term exposure to wildfire smoke is associated with respiratory illnesses, reports on the association between short-term occupational exposure to wildfire smoke and lung function remain scarce. Methods In this cross-sectional study, we analyzed data of 218 Royal Canadian Mounted Police officers (mean age: 38±9 years) deployed at the Fort McMurray wildfire in 2016. Individual exposure to air pollutants was calculated by integrating the duration of exposure with the air quality parameters obtained from the nearest air quality monitoring station during the phase of deployment. Lung function was measured using spirometry and body plethysmography. Association between exposure and lung function was examined using principal component linear regression analysis, adjusting for potential confounders. Results The participants were predominantly male (71%). Mean forced expiratory volume in 1 second (FEV 1 ), and residual volume (RV) were 76.5±5.9 and 80.1±19.5 (% predicted). A marginal association was observed between air pollution and higher RV [β: 1.55; 95%CI: -0.28 to 3.37 per interquartile change of air pollution index], but not with other lung function indices. The association between air pollution index and RV was significantly higher in participants who were screened within the first three months of deployment [2.80; 0.91 to 4.70] than those screened later [-0.28; -2.58 to 2.03], indicating a more acute effect of air pollution on peripheral airways. Conclusion Acute short-term exposure to wildfire-associated air pollutants may impose subtle but clinically important deleterious respiratory effects, particularly in the peripheral airways." @default.
• W3113209092 created "2020-12-21" @default.
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• W3113209092 date "2020-12-18" @default.
• W3113209092 modified "2023-09-27" @default.
• W3113209092 title "Short-term acute exposure to wildfire smoke and lung function in a Royal Canadian Mounted Police (RCMP) cohort" @default.
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• W3113209092 doi "https://doi.org/10.1101/2020.12.15.20248289" @default.
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