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• W3113237225 abstract "<h2>Abstract</h2><h3>Study Objective</h3> To determine clinical and laboratory characteristics of ovarian torsion (OT; n = 28) compared with a non-OT control (OC; n = 64) group. <h3>Design</h3> Retrospective single-center review performed between January 2006 and December 2016. <h3>Setting</h3> Academic department of pediatric surgery. <h3>Participants and Interventions</h3> Postoperative diagnosis of pediatric ovarian pathology (International Classification of Diseases, 10th Revision code N83) in 88 patients who underwent 92 surgeries for suspected OT, aged from 3 days to 17.8 years. <h3>Main Outcome Measures</h3> Predictive value for OT according to biometric, procedural, and laboratory parameters at the time of admission. <h3>Results</h3> Compared with OC, OT in patients aged older than 1 year was associated with elevated values regarding white blood cell count, neutrophils, neutrophil to lymphocyte ratio (NLR; all <i>P</i> < .001), platelet to lymphocyte ratio (PLR; <i>P</i> = .003), platelets (<i>P =</i> .011), and a trend toward raised C-reactive protein (<i>P</i> = .054), whereas lymphocytes and lymphocyte to C-reactive protein ratio (both <i>P</i> < .001) were decreased. Using receiver operating characteristic analysis for differentiating OC from OT, besides lymphocytes and NLR (both area under the curve > 0.9), PLR elicited strongest discriminatory accuracy (area under the curve = 0.946 ± 0.037; <i>P</i> < .001; sensitivity 82%; specificity 90%). At binary logistic regression analysis PLR (<i>P</i> = .018) was independently predictive of OT. OT was suspected on ultrasound imaging in 15/18 (83%), showed a right-sided dominance in 13/18 (72%), and was associated with younger age (<i>P</i> = .003). No differences regarding laboratory or procedural parameters in patients aged younger than 1 year were discerned. <h3>Conclusion</h3> Blood count indices such as PLR, NLR, and lymphocyte to C-reactive protein ratio might be helpful in identification of inflammatory processes as induced by ischemia in OT. Together with ultrasound and clinical features, these parameters constitute potential predictors of OT in girls aged older than 1 year." @default.
• W3113237225 created "2020-12-21" @default.
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• W3113237225 date "2021-06-01" @default.
• W3113237225 modified "2023-09-26" @default.
• W3113237225 title "Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio Might Predict Pediatric Ovarian Torsion: A Single-Institution Experience and Review of the Literature" @default.
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• W3113237225 doi "https://doi.org/10.1016/j.jpag.2020.12.003" @default.
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