FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113242110> ?p ?o ?g. }

• W3113242110 abstract "Low back pain (LBP) is a serious medical condition that affects a large percentage of the population worldwide. One cause of LBP is disc degeneration (DD), which is characterized by progressive breakdown of the disc and an inflamed disc environment. Current treatment options for patients with symptomatic DD are limited and are often unsuccessful, so many patients turn to prescription opioids for pain management in a time when opioid usage, addiction, and drug-related deaths are at an all-time high. In this paper, we discuss the etiology of lumbar DD and currently available treatments, as well as the potential for cell therapy to offer a biologic, non-opioid alternative to patients suffering from the condition. Finally, we present an overview of an investigational cell therapy called IDCT (Injectable Discogenic Cell Therapy), which is currently under evaluation in multiple double-blind clinical trials overseen by major regulatory agencies. The active ingredient in IDCT is a novel allogeneic cell population known as Discogenic Cells. These cells, which are derived from intervertebral disc tissue, have been shown to possess both regenerative and immunomodulatory properties. Cell therapies have unique properties that may ultimately lead to decreased pain and improved function, as well as curb the numbers of patients pursuing opioids. Their efficacy is best assessed in rigorous double-blinded and placebo-controlled clinical studies." @default.
• W3113242110 created "2020-12-21" @default.
• W3113242110 creator A5015809454 @default.
• W3113242110 creator A5021952078 @default.
• W3113242110 creator A5044986583 @default.
• W3113242110 creator A5056083682 @default.
• W3113242110 creator A5056827984 @default.
• W3113242110 creator A5057302250 @default.
• W3113242110 creator A5059664251 @default.
• W3113242110 creator A5077158976 @default.
• W3113242110 date "2020-12-16" @default.
• W3113242110 modified "2023-09-24" @default.
• W3113242110 title "Perspectives on the Treatment of Lumbar Disc Degeneration: The Value Proposition for a Cell-Based Therapy, Immunomodulatory Properties of Discogenic Cells and the Associated Clinical Evaluation Strategy" @default.
• W3113242110 cites W1119061996 @default.
• W3113242110 cites W1520612770 @default.
• W3113242110 cites W1551586706 @default.
• W3113242110 cites W183502252 @default.
• W3113242110 cites W1966188170 @default.
• W3113242110 cites W1972188754 @default.
• W3113242110 cites W1972456273 @default.
• W3113242110 cites W1974495205 @default.
• W3113242110 cites W1987170274 @default.
• W3113242110 cites W1988250393 @default.
• W3113242110 cites W1996794299 @default.
• W3113242110 cites W1997187415 @default.
• W3113242110 cites W2006996324 @default.
• W3113242110 cites W2010368097 @default.
• W3113242110 cites W2016107778 @default.
• W3113242110 cites W2020448162 @default.
• W3113242110 cites W2022837481 @default.
• W3113242110 cites W2027037950 @default.
• W3113242110 cites W2028345823 @default.
• W3113242110 cites W2036755333 @default.
• W3113242110 cites W2050475565 @default.
• W3113242110 cites W2053025121 @default.
• W3113242110 cites W2063547594 @default.
• W3113242110 cites W2067874068 @default.
• W3113242110 cites W2075154931 @default.
• W3113242110 cites W2092798278 @default.
• W3113242110 cites W2108344016 @default.
• W3113242110 cites W2110132004 @default.
• W3113242110 cites W2111887260 @default.
• W3113242110 cites W2115108245 @default.
• W3113242110 cites W2135190328 @default.
• W3113242110 cites W2140617608 @default.
• W3113242110 cites W2143018793 @default.
• W3113242110 cites W2157132102 @default.
• W3113242110 cites W2163854833 @default.
• W3113242110 cites W2167810128 @default.
• W3113242110 cites W2173919164 @default.
• W3113242110 cites W2236473609 @default.
• W3113242110 cites W2238707607 @default.
• W3113242110 cites W2397213886 @default.
• W3113242110 cites W2521591018 @default.
• W3113242110 cites W2591979262 @default.
• W3113242110 cites W2596972615 @default.
• W3113242110 cites W2598850272 @default.
• W3113242110 cites W2771006532 @default.
• W3113242110 cites W2783126104 @default.
• W3113242110 cites W2788205629 @default.
• W3113242110 cites W2801948798 @default.
• W3113242110 cites W2884067445 @default.
• W3113242110 cites W2889771124 @default.
• W3113242110 cites W2890863884 @default.
• W3113242110 cites W2900430054 @default.
• W3113242110 cites W2903012367 @default.
• W3113242110 cites W2969798766 @default.
• W3113242110 cites W2970512250 @default.
• W3113242110 cites W2972147682 @default.
• W3113242110 cites W3009021823 @default.
• W3113242110 cites W3189197737 @default.
• W3113242110 doi "https://doi.org/10.3389/fsurg.2020.554382" @default.
• W3113242110 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7772215" @default.
• W3113242110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33392242" @default.
• W3113242110 hasPublicationYear "2020" @default.
• W3113242110 type Work @default.
• W3113242110 sameAs 3113242110 @default.
• W3113242110 citedByCount "4" @default.
• W3113242110 countsByYear W31132421102021 @default.
• W3113242110 countsByYear W31132421102022 @default.
• W3113242110 countsByYear W31132421102023 @default.
• W3113242110 crossrefType "journal-article" @default.
• W3113242110 hasAuthorship W3113242110A5015809454 @default.
• W3113242110 hasAuthorship W3113242110A5021952078 @default.
• W3113242110 hasAuthorship W3113242110A5044986583 @default.
• W3113242110 hasAuthorship W3113242110A5056083682 @default.
• W3113242110 hasAuthorship W3113242110A5056827984 @default.
• W3113242110 hasAuthorship W3113242110A5057302250 @default.
• W3113242110 hasAuthorship W3113242110A5059664251 @default.
• W3113242110 hasAuthorship W3113242110A5077158976 @default.
• W3113242110 hasBestOaLocation W31132421101 @default.
• W3113242110 hasConcept C10882517 @default.
• W3113242110 hasConcept C126322002 @default.
• W3113242110 hasConcept C141071460 @default.
• W3113242110 hasConcept C142724271 @default.
• W3113242110 hasConcept C1491633281 @default.
• W3113242110 hasConcept C170493617 @default.
• W3113242110 hasConcept C204787440 @default.
• W3113242110 hasConcept C2777755357 @default.
• W3113242110 hasConcept C2780907711 @default.

• next