FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113302535> ?p ?o ?g. }

• W3113302535 abstract "Introduction In the UK, the fasting plasma concentrations of a panel of gut hormones (comprising vasoactive intestinal peptide (VIP), gastrin, pancreatic polypeptide (PP), glucagon, somatostatin and chromogranin A) are measured to evaluate patients who have or who (due to unexplained and compatible symptoms) are suspected of having neuroendocrine tumors (NETs). False positive elevated hormone concentrations are sometimes found. Objective To evaluate the frequency and implications of false positive fasting gut hormone results. Methods Retrospective audit of fasting gut hormone profile results at a large UK university teaching hospital over 12 months. Results Fasting gut hormone concentrations were measured in 231 patients during 2017. No NETs were found in the 88 patients who had this test performed only to investigate symptoms. 31 false positive gastrin, 8 false positive chromogranin A, two false positive glucagon, three false positive somatostatin, one false positive PP, and one false positive VIP results were found. We extended the audit for glucagon and somatostatin for an additional two years and found seven probable false-positive raised glucagon concentrations and four probable false-positive elevated plasma somatostatin concentrations in total. Conclusions False-positive elevations of plasma gastrin and chromogranin A were common and causes such as proton pump inhibitor use or inadequate fasting accounted for most cases. Elevated plasma concentrations of the other gut hormones were also detected in patients who had no other evidence of NET. Other diagnoses (e.g. cirrhosis and medullary thyroid carcinoma for hypersomatostatinemia and type 2 diabetes mellitus, pancreatitis, liver or renal impairment for hyperglucagonemia) may cause these false positive results." @default.
• W3113302535 created "2020-12-21" @default.
• W3113302535 creator A5032754687 @default.
• W3113302535 creator A5036457269 @default.
• W3113302535 creator A5042892802 @default.
• W3113302535 creator A5075373202 @default.
• W3113302535 creator A5078113496 @default.
• W3113302535 date "2020-12-16" @default.
• W3113302535 modified "2023-10-10" @default.
• W3113302535 title "Frequency and Causes of False-Positive Elevated Plasma Concentrations of Fasting Gut Hormones in a Specialist Neuroendocrine Tumor Center" @default.
• W3113302535 cites W1604068098 @default.
• W3113302535 cites W1963514127 @default.
• W3113302535 cites W1968109150 @default.
• W3113302535 cites W1969809022 @default.
• W3113302535 cites W1971066744 @default.
• W3113302535 cites W1973382720 @default.
• W3113302535 cites W1982291147 @default.
• W3113302535 cites W1987774867 @default.
• W3113302535 cites W1997134168 @default.
• W3113302535 cites W1998510639 @default.
• W3113302535 cites W1999242098 @default.
• W3113302535 cites W1999882688 @default.
• W3113302535 cites W2002537556 @default.
• W3113302535 cites W2003946536 @default.
• W3113302535 cites W2030326687 @default.
• W3113302535 cites W2039759833 @default.
• W3113302535 cites W2042072326 @default.
• W3113302535 cites W2051087505 @default.
• W3113302535 cites W2052414387 @default.
• W3113302535 cites W2057263266 @default.
• W3113302535 cites W2071602271 @default.
• W3113302535 cites W2071878457 @default.
• W3113302535 cites W2073439900 @default.
• W3113302535 cites W2077080566 @default.
• W3113302535 cites W2081086802 @default.
• W3113302535 cites W2090412454 @default.
• W3113302535 cites W2090861951 @default.
• W3113302535 cites W2108596199 @default.
• W3113302535 cites W2114591228 @default.
• W3113302535 cites W2118268599 @default.
• W3113302535 cites W2136110142 @default.
• W3113302535 cites W2146946075 @default.
• W3113302535 cites W2150279099 @default.
• W3113302535 cites W2155323919 @default.
• W3113302535 cites W2157094152 @default.
• W3113302535 cites W2160177254 @default.
• W3113302535 cites W2211536246 @default.
• W3113302535 cites W2225295951 @default.
• W3113302535 cites W2313906982 @default.
• W3113302535 cites W2328336350 @default.
• W3113302535 cites W2409034926 @default.
• W3113302535 cites W2415943230 @default.
• W3113302535 cites W2555067145 @default.
• W3113302535 cites W2608160487 @default.
• W3113302535 cites W2792932273 @default.
• W3113302535 cites W2898466542 @default.
• W3113302535 cites W2902059415 @default.
• W3113302535 cites W2905402457 @default.
• W3113302535 cites W2978270329 @default.
• W3113302535 cites W4229970565 @default.
• W3113302535 cites W4232835297 @default.
• W3113302535 cites W4246037574 @default.
• W3113302535 doi "https://doi.org/10.3389/fendo.2020.606264" @default.
• W3113302535 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7774602" @default.
• W3113302535 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33391185" @default.
• W3113302535 hasPublicationYear "2020" @default.
• W3113302535 type Work @default.
• W3113302535 sameAs 3113302535 @default.
• W3113302535 citedByCount "4" @default.
• W3113302535 countsByYear W31133025352021 @default.
• W3113302535 countsByYear W31133025352022 @default.
• W3113302535 countsByYear W31133025352023 @default.
• W3113302535 crossrefType "journal-article" @default.
• W3113302535 hasAuthorship W3113302535A5032754687 @default.
• W3113302535 hasAuthorship W3113302535A5036457269 @default.
• W3113302535 hasAuthorship W3113302535A5042892802 @default.
• W3113302535 hasAuthorship W3113302535A5075373202 @default.
• W3113302535 hasAuthorship W3113302535A5078113496 @default.
• W3113302535 hasBestOaLocation W31133025351 @default.
• W3113302535 hasConcept C118303440 @default.
• W3113302535 hasConcept C126322002 @default.
• W3113302535 hasConcept C134018914 @default.
• W3113302535 hasConcept C170493617 @default.
• W3113302535 hasConcept C204232928 @default.
• W3113302535 hasConcept C2776297358 @default.
• W3113302535 hasConcept C2776986829 @default.
• W3113302535 hasConcept C2778108375 @default.
• W3113302535 hasConcept C2778563252 @default.
• W3113302535 hasConcept C2781025020 @default.
• W3113302535 hasConcept C49039625 @default.
• W3113302535 hasConcept C71315377 @default.
• W3113302535 hasConcept C71924100 @default.
• W3113302535 hasConcept C77231918 @default.
• W3113302535 hasConcept C8330315 @default.
• W3113302535 hasConcept C90924648 @default.
• W3113302535 hasConceptScore W3113302535C118303440 @default.
• W3113302535 hasConceptScore W3113302535C126322002 @default.
• W3113302535 hasConceptScore W3113302535C134018914 @default.
• W3113302535 hasConceptScore W3113302535C170493617 @default.
• W3113302535 hasConceptScore W3113302535C204232928 @default.

• next