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- W3113478112 abstract "Background and Aims: Atherosclerosis of human major vessels is often a morphological basis of mortality from cardiovascular diseases. In this pathology intima of arteries is damaged, luminal occlusion occurs and blood supply to organs is deteriorated. Atherosclerosis is difficult to recognize in early stages. Molecular genetic markers could help the diagnostics of this disease. The aim of the present article was the detection of threshold heteroplasmy level of mtDNA mutations, after reaching which in a patient appeared atherosclerotic lesions. Besides, this parameter was detected for mutations, in which after reaching threshold heteroplasmy level, a protective antiatherogenic effect started to appear." @default.
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- W3113478112 date "2020-12-01" @default.
- W3113478112 modified "2023-10-18" @default.
- W3113478112 title "Original markers of atherosclerosis: Threshold levels of heteroplasmy mutations mtDNA" @default.
- W3113478112 doi "https://doi.org/10.1016/j.atherosclerosis.2020.10.341" @default.
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