FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3113706031> ?p ?o ?g. }

• W3113706031 endingPage "5" @default.
• W3113706031 startingPage "5" @default.
• W3113706031 abstract "Tick vaccination is an environmentally friendly alternative for tick control, pathogen infection, and transmission. Tick vaccine protection is sometimes incomplete, which may be due to problems in the stability, conformation, and activity of antibodies. This might be related to oxidative stress, but more studies are needed about the possible relationships between oxidative stress and immune function. The objective of this study was to evaluate and compare various serum biomarkers of antioxidant response and oxidative damage in cattle vaccinated with two recombinant antigens, the chimera of Subolesin- BM95 (homologue antigen of BM86)-MSP1a and BM86, and a control consisting in the adjuvant of the vaccines. Cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of the plasma (FRAP), trolox equivalent antioxidant capacity (TEAC), total thiol concentrations, and uric acid were evaluated in serum to determine the antioxidant response. To evaluate oxidative status, ferrous oxidation-xylenol orange (FOX), total oxidant status (TOS), advanced oxidation protein products (AOPP) and hydrogen peroxide (H2O2) concentrations in serum were determined. In addition, correlations between biomarkers of oxidative stress and antibody titers were evaluated. A significant decrease in all antioxidant biomarkers, with exception of thiol, and also a decrease in the oxidant markers TOS, AOPP and H2O2 was observed in cattle vaccinated with BM86, that also showed the highest antibody titers response whereas no significant differences in any of the biomarkers were detected in the Subolesin-Bm95-MSP1a and control groups. In addition, the dynamics of Cuprac and H2O2 with time showed significant differences between the groups. Although this is a pilot study and the results should be interpreted with caution and corroborated by studies involving a large number of animals, our results indicate that, in our experimental conditions, those vaccines able to induce a lower oxidative stress produce a higher concentration of antigen-specific antibodies. Overall, the results of the study provided information on the behavior of different biomarkers related to antioxidant defense, and the oxidative damage in cattle in response to vaccination." @default.
• W3113706031 created "2021-01-05" @default.
• W3113706031 creator A5014244717 @default.
• W3113706031 creator A5045307508 @default.
• W3113706031 creator A5050707715 @default.
• W3113706031 creator A5059973854 @default.
• W3113706031 creator A5062438511 @default.
• W3113706031 creator A5064603712 @default.
• W3113706031 creator A5071688867 @default.
• W3113706031 date "2020-12-24" @default.
• W3113706031 modified "2023-09-26" @default.
• W3113706031 title "Changes in Serum Biomarkers of Oxidative Stress in Cattle Vaccinated with Tick Recombinant Antigens: A Pilot Study" @default.
• W3113706031 cites W1808310697 @default.
• W3113706031 cites W1933315991 @default.
• W3113706031 cites W1966600223 @default.
• W3113706031 cites W1969188080 @default.
• W3113706031 cites W1976464405 @default.
• W3113706031 cites W1978424616 @default.
• W3113706031 cites W1980174454 @default.
• W3113706031 cites W1986440565 @default.
• W3113706031 cites W1987445478 @default.
• W3113706031 cites W2000429341 @default.
• W3113706031 cites W2007974136 @default.
• W3113706031 cites W2019819611 @default.
• W3113706031 cites W2028353549 @default.
• W3113706031 cites W2042641359 @default.
• W3113706031 cites W2049871526 @default.
• W3113706031 cites W2050379759 @default.
• W3113706031 cites W2050413605 @default.
• W3113706031 cites W2052751122 @default.
• W3113706031 cites W2055016945 @default.
• W3113706031 cites W2075206470 @default.
• W3113706031 cites W2082083532 @default.
• W3113706031 cites W2091189156 @default.
• W3113706031 cites W2091362651 @default.
• W3113706031 cites W2094617581 @default.
• W3113706031 cites W2104256799 @default.
• W3113706031 cites W2156682025 @default.
• W3113706031 cites W2165292984 @default.
• W3113706031 cites W2205614565 @default.
• W3113706031 cites W2219403692 @default.
• W3113706031 cites W2335217992 @default.
• W3113706031 cites W2396850114 @default.
• W3113706031 cites W2498899611 @default.
• W3113706031 cites W2519076109 @default.
• W3113706031 cites W2759832410 @default.
• W3113706031 cites W2793231104 @default.
• W3113706031 cites W2797020286 @default.
• W3113706031 cites W2797540534 @default.
• W3113706031 cites W2892674718 @default.
• W3113706031 cites W2898230420 @default.
• W3113706031 cites W2899648713 @default.
• W3113706031 cites W2912161249 @default.
• W3113706031 cites W2943995462 @default.
• W3113706031 cites W2951546673 @default.
• W3113706031 cites W3036191371 @default.
• W3113706031 cites W3054337535 @default.
• W3113706031 cites W3092962412 @default.
• W3113706031 cites W4238319848 @default.
• W3113706031 cites W4361868858 @default.
• W3113706031 cites W73347127 @default.
• W3113706031 doi "https://doi.org/10.3390/vaccines9010005" @default.
• W3113706031 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7824418" @default.
• W3113706031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33374141" @default.
• W3113706031 hasPublicationYear "2020" @default.
• W3113706031 type Work @default.
• W3113706031 sameAs 3113706031 @default.
• W3113706031 citedByCount "7" @default.
• W3113706031 countsByYear W31137060312022 @default.
• W3113706031 countsByYear W31137060312023 @default.
• W3113706031 crossrefType "journal-article" @default.
• W3113706031 hasAuthorship W3113706031A5014244717 @default.
• W3113706031 hasAuthorship W3113706031A5045307508 @default.
• W3113706031 hasAuthorship W3113706031A5050707715 @default.
• W3113706031 hasAuthorship W3113706031A5059973854 @default.
• W3113706031 hasAuthorship W3113706031A5062438511 @default.
• W3113706031 hasAuthorship W3113706031A5064603712 @default.
• W3113706031 hasAuthorship W3113706031A5071688867 @default.
• W3113706031 hasBestOaLocation W31137060311 @default.
• W3113706031 hasConcept C147483822 @default.
• W3113706031 hasConcept C159654299 @default.
• W3113706031 hasConcept C185592680 @default.
• W3113706031 hasConcept C203014093 @default.
• W3113706031 hasConcept C22889606 @default.
• W3113706031 hasConcept C2776151105 @default.
• W3113706031 hasConcept C2777863537 @default.
• W3113706031 hasConcept C2778004101 @default.
• W3113706031 hasConcept C2781150145 @default.
• W3113706031 hasConcept C2993539680 @default.
• W3113706031 hasConcept C32611913 @default.
• W3113706031 hasConcept C55493867 @default.
• W3113706031 hasConcept C86803240 @default.
• W3113706031 hasConceptScore W3113706031C147483822 @default.
• W3113706031 hasConceptScore W3113706031C159654299 @default.
• W3113706031 hasConceptScore W3113706031C185592680 @default.
• W3113706031 hasConceptScore W3113706031C203014093 @default.
• W3113706031 hasConceptScore W3113706031C22889606 @default.
• W3113706031 hasConceptScore W3113706031C2776151105 @default.

• next