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- W3114015919 endingPage "107737" @default.
- W3114015919 startingPage "107737" @default.
- W3114015919 abstract "Mentalizing is an important aspect of social cognition and people vary in their ability to mentalize. Despite initial evidence that mentalizing continues to develop throughout adolescence, it is unclear which neural mechanisms underlie individual variability in mentalizing ability in adolescents. Interactions within and between the default-mode network (DMN), frontoparietal network (FPN) and cingulo-opercular/salience network (CO/SN) have been related to inter-individual differences in cognitive processes in both adults and adolescents. Here, we investigated whether intrinsic connectivity within and between these brain networks explained inter-individual differences in affective mentalizing ability in adolescents. Resting-state brain activity was measured using functional MRI and affective mentalizing ability was defined as correct performance on the Reading the Mind in the Eyes test performed outside the scanner. We identified the DMN, FPN and CO/SN, and within and between network connectivity values were submitted to a bootstrapping enhanced penalized multiple regression analysis to predict mentalizing in 66 young adolescents (11–14 years). We showed that stronger connectivity between the DMN and the FPN, together with lower within-network connectivity of the FPN and the CO/SN predicted better mentalizing performance. These novel findings provide insight into the normative developmental trajectory of the neural mechanisms underlying affective mentalizing in early adolescence." @default.
- W3114015919 created "2021-01-05" @default.
- W3114015919 creator A5001338952 @default.
- W3114015919 creator A5001783758 @default.
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- W3114015919 creator A5051708068 @default.
- W3114015919 creator A5053393561 @default.
- W3114015919 creator A5067364941 @default.
- W3114015919 date "2021-01-01" @default.
- W3114015919 modified "2023-10-01" @default.
- W3114015919 title "Intrinsic network interactions explain individual differences in mentalizing ability in adolescents" @default.
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