FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3114060604> ?p ?o ?g. }

• W3114060604 endingPage "393" @default.
• W3114060604 startingPage "393" @default.
• W3114060604 abstract ": Rheumatoid artherits (RA) is a refractory disease and the imbalance between pro- and anti-inflammatory cytokines in favor of pro-inflammatory cytokines has been implicated in pathogenesis of RA. In this context, the aim of the present study was to compare the anti-inflammatory and antioxidant effects of candesartan, an angiotensin-receptor blocker, and atorvastatin in RA patients.: In this single-blinded parallel randomized placebo controlled study, the patients recruited between December 2017 and May 2018 were categorized into three groups: group 1 included 15 RA patients who served as control group and received traditional therapy (+ placebo); group 2 included 15 RA patients who received traditional therapy + candesartan (8 mg/day); and group 3 included 15 patients who received traditional therapy + atorvastatin (20 mg/day) for three months. Clinical status in RA patients was evaluated by Disease Activity Score 28 (DAS28), Health Assessment Questionnaire-Disability Index (HAQ-DI) and morning stiffness before and three months after treatment. All groups were subjected to biochemical analysis of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumour necrosis factor-alpha (TNF-α), interleukin-1beta (IL-1β) and malondialdehyde (MDA) before and three months after treatment.: Both candesartan and atorvastatin treated groups showed significant decrease in serum levels IL-1β and TNF-α, acute-phase reactants (CRP and ESR), number of swollen joint and patient global assessment. This was also associated with improvement in disease activity and quality of life regarding DAS28 and HAQ-DI as compared to baseline data and the control group. Atorvastatin group showed significant decrease in the serum level of oxidative stress marker (MDA).: Both candesartan and atorvastatin showed anti-inflammatory effect and immunomodulatory effects leading to improvement in clinical status and disease activity in RA patients. However, atorvastatin was superior to candesartan through its anti-oxidant effect." @default.
• W3114060604 created "2021-01-05" @default.
• W3114060604 creator A5004843558 @default.
• W3114060604 creator A5013522777 @default.
• W3114060604 creator A5037398177 @default.
• W3114060604 creator A5061468370 @default.
• W3114060604 creator A5066862132 @default.
• W3114060604 date "2020-01-01" @default.
• W3114060604 modified "2023-10-12" @default.
• W3114060604 title "A comparative study on the anti-inflammatory effect of angiotensin-receptor blockers & statins on rheumatoid arthritis disease activity" @default.
• W3114060604 cites W1479880028 @default.
• W3114060604 cites W1495554157 @default.
• W3114060604 cites W1682953706 @default.
• W3114060604 cites W192193895 @default.
• W3114060604 cites W1970459010 @default.
• W3114060604 cites W1978087024 @default.
• W3114060604 cites W2004843485 @default.
• W3114060604 cites W2007954685 @default.
• W3114060604 cites W2023313940 @default.
• W3114060604 cites W2031550562 @default.
• W3114060604 cites W2044651570 @default.
• W3114060604 cites W2048938982 @default.
• W3114060604 cites W2056561920 @default.
• W3114060604 cites W2070031257 @default.
• W3114060604 cites W2070396041 @default.
• W3114060604 cites W2075677954 @default.
• W3114060604 cites W2090150130 @default.
• W3114060604 cites W2106171259 @default.
• W3114060604 cites W2117853190 @default.
• W3114060604 cites W2120778240 @default.
• W3114060604 cites W2126063422 @default.
• W3114060604 cites W2128921112 @default.
• W3114060604 cites W2128952811 @default.
• W3114060604 cites W2138673524 @default.
• W3114060604 cites W2145087007 @default.
• W3114060604 cites W2273452210 @default.
• W3114060604 cites W2346664883 @default.
• W3114060604 cites W2415793789 @default.
• W3114060604 cites W2521967881 @default.
• W3114060604 cites W2592199962 @default.
• W3114060604 cites W2788084781 @default.
• W3114060604 cites W4238801120 @default.
• W3114060604 doi "https://doi.org/10.4103/ijmr.ijmr_640_19" @default.
• W3114060604 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8061595" @default.
• W3114060604 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33380704" @default.
• W3114060604 hasPublicationYear "2020" @default.
• W3114060604 type Work @default.
• W3114060604 sameAs 3114060604 @default.
• W3114060604 citedByCount "6" @default.
• W3114060604 countsByYear W31140606042021 @default.
• W3114060604 countsByYear W31140606042022 @default.
• W3114060604 countsByYear W31140606042023 @default.
• W3114060604 crossrefType "journal-article" @default.
• W3114060604 hasAuthorship W3114060604A5004843558 @default.
• W3114060604 hasAuthorship W3114060604A5013522777 @default.
• W3114060604 hasAuthorship W3114060604A5037398177 @default.
• W3114060604 hasAuthorship W3114060604A5061468370 @default.
• W3114060604 hasAuthorship W3114060604A5066862132 @default.
• W3114060604 hasBestOaLocation W31140606041 @default.
• W3114060604 hasConcept C126322002 @default.
• W3114060604 hasConcept C142724271 @default.
• W3114060604 hasConcept C151730666 @default.
• W3114060604 hasConcept C170493617 @default.
• W3114060604 hasConcept C204787440 @default.
• W3114060604 hasConcept C27081682 @default.
• W3114060604 hasConcept C2777482532 @default.
• W3114060604 hasConcept C2777575956 @default.
• W3114060604 hasConcept C2778143017 @default.
• W3114060604 hasConcept C2779343474 @default.
• W3114060604 hasConcept C2780036600 @default.
• W3114060604 hasConcept C2780132546 @default.
• W3114060604 hasConcept C2908929049 @default.
• W3114060604 hasConcept C71924100 @default.
• W3114060604 hasConcept C86803240 @default.
• W3114060604 hasConcept C90924648 @default.
• W3114060604 hasConceptScore W3114060604C126322002 @default.
• W3114060604 hasConceptScore W3114060604C142724271 @default.
• W3114060604 hasConceptScore W3114060604C151730666 @default.
• W3114060604 hasConceptScore W3114060604C170493617 @default.
• W3114060604 hasConceptScore W3114060604C204787440 @default.
• W3114060604 hasConceptScore W3114060604C27081682 @default.
• W3114060604 hasConceptScore W3114060604C2777482532 @default.
• W3114060604 hasConceptScore W3114060604C2777575956 @default.
• W3114060604 hasConceptScore W3114060604C2778143017 @default.
• W3114060604 hasConceptScore W3114060604C2779343474 @default.
• W3114060604 hasConceptScore W3114060604C2780036600 @default.
• W3114060604 hasConceptScore W3114060604C2780132546 @default.
• W3114060604 hasConceptScore W3114060604C2908929049 @default.
• W3114060604 hasConceptScore W3114060604C71924100 @default.
• W3114060604 hasConceptScore W3114060604C86803240 @default.
• W3114060604 hasConceptScore W3114060604C90924648 @default.
• W3114060604 hasIssue "4" @default.
• W3114060604 hasLocation W31140606041 @default.
• W3114060604 hasLocation W31140606042 @default.
• W3114060604 hasLocation W31140606043 @default.
• W3114060604 hasLocation W31140606044 @default.
• W3114060604 hasOpenAccess W3114060604 @default.
• W3114060604 hasPrimaryLocation W31140606041 @default.

• next