FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3114367931> ?p ?o ?g. }

• W3114367931 endingPage "691" @default.
• W3114367931 startingPage "682" @default.
• W3114367931 abstract "Antihypertensive drug treatment is cost-effective for adults at high risk of developing cardiovascular disease (CVD). However, the cost-effectiveness in people with stage 1 hypertension (140–159 mm Hg systolic blood pressure) at lower CVD risk remains unclear. The objective was to establish the 10-year CVD risk threshold where initiating antihypertensive drug treatment for primary prevention in adults, with stage 1 hypertension, becomes cost-effective. A lifetime horizon Markov model compared antihypertensive drug versus no treatment, using a UK National Health Service perspective. Analyses were conducted for groups ranging between 5% and 20% 10-year CVD risk. Health states included no CVD event, CVD and non-CVD death, and 6 nonfatal CVD morbidities. Interventions were compared using cost-per-quality-adjusted life-years. The base-case age was 60, with analyses repeated between ages 40 and 75. The model was run separately for men and women, and threshold CVD risk assessed against the minimum plausible risk for each group. Treatment was cost-effective at 10% CVD risk for both sexes (incremental cost-effectiveness ratio £10 017/quality-adjusted life-year [$14 542] men, £8635/QALY [$12 536] women) in the base-case. The result was robust in probabilistic and deterministic sensitivity analyses but was sensitive to treatment effects. Treatment was cost-effective for men regardless of age and women aged >60. Initiating treatment in stage 1 hypertension for people aged 60 is cost-effective regardless of 10-year CVD risk. For other age groups, it is also cost-effective to treat regardless of risk, except in younger women." @default.
• W3114367931 created "2021-01-05" @default.
• W3114367931 creator A5041732299 @default.
• W3114367931 creator A5061421992 @default.
• W3114367931 creator A5066079193 @default.
• W3114367931 creator A5067220564 @default.
• W3114367931 creator A5079750619 @default.
• W3114367931 creator A5087460590 @default.
• W3114367931 date "2021-02-01" @default.
• W3114367931 modified "2023-09-27" @default.
• W3114367931 title "Cost-Effectiveness of Initiating Pharmacological Treatment in Stage One Hypertension Based on 10-Year Cardiovascular Disease Risk" @default.
• W3114367931 cites W1497461844 @default.
• W3114367931 cites W2024418303 @default.
• W3114367931 cites W2054796764 @default.
• W3114367931 cites W2055838663 @default.
• W3114367931 cites W2114529215 @default.
• W3114367931 cites W2123974278 @default.
• W3114367931 cites W2138585828 @default.
• W3114367931 cites W2140191398 @default.
• W3114367931 cites W2141933943 @default.
• W3114367931 cites W2145378489 @default.
• W3114367931 cites W2293263871 @default.
• W3114367931 cites W2549049170 @default.
• W3114367931 cites W2572331255 @default.
• W3114367931 cites W2582461952 @default.
• W3114367931 cites W2618596952 @default.
• W3114367931 cites W2769157921 @default.
• W3114367931 cites W2769574669 @default.
• W3114367931 cites W2898687524 @default.
• W3114367931 cites W2912533302 @default.
• W3114367931 cites W2946535940 @default.
• W3114367931 cites W2964036745 @default.
• W3114367931 cites W2965947914 @default.
• W3114367931 cites W2979596735 @default.
• W3114367931 cites W2981215886 @default.
• W3114367931 cites W2996429394 @default.
• W3114367931 cites W3150595609 @default.
• W3114367931 cites W4247956072 @default.
• W3114367931 doi "https://doi.org/10.1161/hypertensionaha.120.14913" @default.
• W3114367931 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7803450" @default.
• W3114367931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33342242" @default.
• W3114367931 hasPublicationYear "2021" @default.
• W3114367931 type Work @default.
• W3114367931 sameAs 3114367931 @default.
• W3114367931 citedByCount "6" @default.
• W3114367931 countsByYear W31143679312021 @default.
• W3114367931 countsByYear W31143679312022 @default.
• W3114367931 countsByYear W31143679312023 @default.
• W3114367931 crossrefType "journal-article" @default.
• W3114367931 hasAuthorship W3114367931A5041732299 @default.
• W3114367931 hasAuthorship W3114367931A5061421992 @default.
• W3114367931 hasAuthorship W3114367931A5066079193 @default.
• W3114367931 hasAuthorship W3114367931A5067220564 @default.
• W3114367931 hasAuthorship W3114367931A5079750619 @default.
• W3114367931 hasAuthorship W3114367931A5087460590 @default.
• W3114367931 hasBestOaLocation W31143679311 @default.
• W3114367931 hasConcept C112930515 @default.
• W3114367931 hasConcept C118552586 @default.
• W3114367931 hasConcept C126322002 @default.
• W3114367931 hasConcept C159110408 @default.
• W3114367931 hasConcept C1862650 @default.
• W3114367931 hasConcept C27415008 @default.
• W3114367931 hasConcept C2779134260 @default.
• W3114367931 hasConcept C2779951463 @default.
• W3114367931 hasConcept C3019080777 @default.
• W3114367931 hasConcept C64332521 @default.
• W3114367931 hasConcept C71924100 @default.
• W3114367931 hasConcept C84393581 @default.
• W3114367931 hasConceptScore W3114367931C112930515 @default.
• W3114367931 hasConceptScore W3114367931C118552586 @default.
• W3114367931 hasConceptScore W3114367931C126322002 @default.
• W3114367931 hasConceptScore W3114367931C159110408 @default.
• W3114367931 hasConceptScore W3114367931C1862650 @default.
• W3114367931 hasConceptScore W3114367931C27415008 @default.
• W3114367931 hasConceptScore W3114367931C2779134260 @default.
• W3114367931 hasConceptScore W3114367931C2779951463 @default.
• W3114367931 hasConceptScore W3114367931C3019080777 @default.
• W3114367931 hasConceptScore W3114367931C64332521 @default.
• W3114367931 hasConceptScore W3114367931C71924100 @default.
• W3114367931 hasConceptScore W3114367931C84393581 @default.
• W3114367931 hasIssue "2" @default.
• W3114367931 hasLocation W31143679311 @default.
• W3114367931 hasLocation W31143679312 @default.
• W3114367931 hasLocation W31143679313 @default.
• W3114367931 hasLocation W31143679314 @default.
• W3114367931 hasLocation W31143679315 @default.
• W3114367931 hasOpenAccess W3114367931 @default.
• W3114367931 hasPrimaryLocation W31143679311 @default.
• W3114367931 hasRelatedWork W1982007038 @default.
• W3114367931 hasRelatedWork W2043028331 @default.
• W3114367931 hasRelatedWork W2043144072 @default.
• W3114367931 hasRelatedWork W2069915399 @default.
• W3114367931 hasRelatedWork W2126569537 @default.
• W3114367931 hasRelatedWork W2310170993 @default.
• W3114367931 hasRelatedWork W2330972598 @default.
• W3114367931 hasRelatedWork W2526370100 @default.
• W3114367931 hasRelatedWork W2563184539 @default.
• W3114367931 hasRelatedWork W2989475533 @default.

• next