FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3114371388> ?p ?o ?g. }

• W3114371388 endingPage "164" @default.
• W3114371388 startingPage "164" @default.
• W3114371388 abstract "164 Objectives: Radiomics is based on extracting high throughput quantitative features from images in order to better characterize pathophysiological and physiological process. [1, 2]. Normal tissue radoimics has not been well studied. We investigated radiomic signatures of the liver in healthy subjects on 18-FDG-PET, and compared different liver segmentation strategies and their effect on the consistency of quantitative imaging features (QIF). Methods: Whole body 18 FDG-PET images were obtained from 23 healthy (20 women and 3 men; mean age ± SD, 23.65 ± 3.57 y) subjects who were scanned after total body cooling procedure for 90 minutes prior to scan. We applied 3 methods of segmentation on PET/CT: 1)-segmenting the whole liver, 2)- segmenting 3 consecutive slices at the level of porta hepatis on axial plane(3S) 3)-segmenting a 3cm diameter sphere in Right hepatic lobe (PERCIST liver VOI). 82 QIFs were extracted using pyradiomics software (http://pyradiomics.readthedocs.io).[3] The consistency of features amongst different segmentation methods was assessed by the interclass correlation coefficient(ICC). The reproducibility of FDG PET QIFs was compared by one-sided paired Wilcoxon rank test. Upon determining the more reliable segmentation method, we compared consistency of each individual QIF family of that method using Kruskal-Wallis H Test. To elucidate the association between all QIFs to better characterize the radiomic phenotype of normal liver, a heat map analysis with hierarchical clustering on median centered QIFs using complete linkage while using Pearson9s correlation coefficient as the similarity measure.Results: 26 QIFs had high reproducibility (ICC > 0.8) between the QIFs extracted from 3S and whole liver Segmentation, while only 14 QIF showed high reproducibility between the QIFs extracted from the sphere and whole liver segmentation. 3S segmentation had significantly higher reproducibility (ICC=0.57±0.32, p-value≍0.9 X 10-10) compared to Sphere segmentation (ICC=0.29±0.34).Reliability of Gray Level Co-occurrence Matrix (GLCM, ICC=0.77±0.24), Gray Level Size Zone Matrix (GLSZM,ICC= 0.28±0.22), Gray Level Run Length Matrix (GLRLM, 0.51±0.29), Neighbouring Gray Tone Difference Matrix (NGTDM, 0.1±0.05) Gray Level Dependence Matrix (GLDM, 0.49±0.29) intensity values (ICC= 0.79±0.22) extracted from 3S segmentation showed significant difference based on Kruskal-Wallis H Test (p-value ≍ 0.14 X 10 -5 ).11 distinct clusters were identified from QIF extracted from the whole liver. Conclusions: 3S segmentation showed considerable reliability for GLCM and 1st order intensity values and can be considered as a rapid alternative to whole liver segmentation for extracting FDG PET radiomic features. Liver PET radiomic signature in healthy subjects provide us with reference values to compare with liver radiomic phenotypes from different liver pathologies and systemic disorders." @default.
• W3114371388 created "2021-01-05" @default.
• W3114371388 creator A5024722162 @default.
• W3114371388 creator A5029560285 @default.
• W3114371388 creator A5088698596 @default.
• W3114371388 date "2018-05-01" @default.
• W3114371388 modified "2023-09-26" @default.
• W3114371388 title "FDG PET Radiomic Signature of Normal Liver and its Reproducibility using different Segmentation Strategies" @default.
• W3114371388 hasPublicationYear "2018" @default.
• W3114371388 type Work @default.
• W3114371388 sameAs 3114371388 @default.
• W3114371388 citedByCount "0" @default.
• W3114371388 crossrefType "journal-article" @default.
• W3114371388 hasAuthorship W3114371388A5024722162 @default.
• W3114371388 hasAuthorship W3114371388A5029560285 @default.
• W3114371388 hasAuthorship W3114371388A5088698596 @default.
• W3114371388 hasConcept C104709138 @default.
• W3114371388 hasConcept C105795698 @default.
• W3114371388 hasConcept C126322002 @default.
• W3114371388 hasConcept C12868164 @default.
• W3114371388 hasConcept C154945302 @default.
• W3114371388 hasConcept C206041023 @default.
• W3114371388 hasConcept C2776436953 @default.
• W3114371388 hasConcept C2989005 @default.
• W3114371388 hasConcept C33923547 @default.
• W3114371388 hasConcept C41008148 @default.
• W3114371388 hasConcept C69941244 @default.
• W3114371388 hasConcept C71924100 @default.
• W3114371388 hasConcept C89600930 @default.
• W3114371388 hasConcept C9893847 @default.
• W3114371388 hasConceptScore W3114371388C104709138 @default.
• W3114371388 hasConceptScore W3114371388C105795698 @default.
• W3114371388 hasConceptScore W3114371388C126322002 @default.
• W3114371388 hasConceptScore W3114371388C12868164 @default.
• W3114371388 hasConceptScore W3114371388C154945302 @default.
• W3114371388 hasConceptScore W3114371388C206041023 @default.
• W3114371388 hasConceptScore W3114371388C2776436953 @default.
• W3114371388 hasConceptScore W3114371388C2989005 @default.
• W3114371388 hasConceptScore W3114371388C33923547 @default.
• W3114371388 hasConceptScore W3114371388C41008148 @default.
• W3114371388 hasConceptScore W3114371388C69941244 @default.
• W3114371388 hasConceptScore W3114371388C71924100 @default.
• W3114371388 hasConceptScore W3114371388C89600930 @default.
• W3114371388 hasConceptScore W3114371388C9893847 @default.
• W3114371388 hasLocation W31143713881 @default.
• W3114371388 hasOpenAccess W3114371388 @default.
• W3114371388 hasPrimaryLocation W31143713881 @default.
• W3114371388 hasRelatedWork W2059939049 @default.
• W3114371388 hasRelatedWork W2103851997 @default.
• W3114371388 hasRelatedWork W2324083726 @default.
• W3114371388 hasRelatedWork W2473959085 @default.
• W3114371388 hasRelatedWork W2501227799 @default.
• W3114371388 hasRelatedWork W2532362258 @default.
• W3114371388 hasRelatedWork W2739046037 @default.
• W3114371388 hasRelatedWork W2755129255 @default.
• W3114371388 hasRelatedWork W2908574839 @default.
• W3114371388 hasRelatedWork W2912550564 @default.
• W3114371388 hasRelatedWork W2921137012 @default.
• W3114371388 hasRelatedWork W2972313349 @default.
• W3114371388 hasRelatedWork W2996500840 @default.
• W3114371388 hasRelatedWork W3039802208 @default.
• W3114371388 hasRelatedWork W3087358770 @default.
• W3114371388 hasRelatedWork W3091185828 @default.
• W3114371388 hasRelatedWork W3122128302 @default.
• W3114371388 hasRelatedWork W3133297330 @default.
• W3114371388 hasRelatedWork W3165545946 @default.
• W3114371388 hasRelatedWork W3182986461 @default.
• W3114371388 hasVolume "59" @default.
• W3114371388 isParatext "false" @default.
• W3114371388 isRetracted "false" @default.
• W3114371388 magId "3114371388" @default.
• W3114371388 workType "article" @default.