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• W3114501713 abstract "Angelicae Sinensis Radix is a world-renowned herbal medicine originating in China. Owing to many environmental and geographical factors, Angelicae Sinensis Radix from various origins may have a difference in the content of ingredients, which made the confusion in the clinical practice and market. Herein, a binary chromatographic fingerprinting analysis method is developed via hydrophilic interaction chromatography and reversed-phase liquid chromatography to obtain more chemical information. Following that, an ultra-performance liquid chromatography with a triple quadrupole mass spectrometry method is furnished to simultaneously detect 17 ingredients of Angelicae Sinensis Radix gathered from six geographic zones in China. Eventually, the principal component analysis is successfully carried out to classify and differentiate the Angelicae Sinensis Radix from different origins, meanwhile the quantitative volcano plots was used to observe the changes of ingredient trends vividly. Accordingly, the proposed binary chromatography and triple quadrupole tandem mass spectrometry coupled with multivariate statistical analysis can be utilized as a facile and reliable method for origin tracing and quality control of Angelicae Sinensis Radix." @default.
• W3114501713 created "2021-01-05" @default.
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• W3114501713 date "2021-01-26" @default.
• W3114501713 modified "2023-10-10" @default.
• W3114501713 title "Quality assessment and traceability study of <i>Angelicae Sinensis Radix</i> via binary chromatography, triple quadrupole tandem mass spectrometry, and multivariate statistical analysis" @default.
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• W3114501713 doi "https://doi.org/10.1002/jssc.202001087" @default.
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