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- W3114686803 abstract "2045 Objectives: Glomerular filtration rate (GFR) has become an increasingly important factor in assessing overall renal perfusion and function. Currently, the Society of Nuclear Medicine and Molecular Imaging (SNMMI) has no specific protocol for retrieving GFR and therefore nuclear medicine (NM) departments follow varying protocols. Common practice for many NM departments includes retrieving a plasma sample and then collecting an additional filtered plasma sample termed “ultrafiltrate” at one and three hours post-injection. Then, a final GFR is reported based on the three hour post-injection ultrafiltrate sample. The purpose of this research study is to compare unfiltered plasma GFR values and ultrafiltrate GFR values in order to evaluate whether collecting an additional filtered plasma sample is necessary and beneficial. Methods: Following HIPPA guidelines, body surface area corrected GFR values recorded between June 2016 and October 2018 were collected retrospectively from 180 patient charts. Values including three hours post-injection plasma GFR and three hours post-injection ultrafiltrate GFR (cc/min) were recorded and compared utilizing a paired t-test. The difference between each value was then quantified utilizing a percent change calculation. Results: The paired t-test yielded a t-critical value of 1.650 at an alpha level of 0.05 for 179 degrees of freedom and a p-value of <0.001. The average percent increase in GFR between plasma samples and ultra-filtered samples was 6.049% with a standard deviation of 0.076%. Conclusions: Because the paired t-test produced a p-value of" @default.
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- W3114686803 date "2019-05-01" @default.
- W3114686803 modified "2023-09-26" @default.
- W3114686803 title "Evaluating the necessity of collecting ultra-filtered plasma samples in determining glomerular filtration rate values." @default.
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