Matches in SemOpenAlex for { <https://semopenalex.org/work/W3114752783> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W3114752783 abstract "Abstract Scrub typhus (ST), caused with the infection of Orientia tsutsugamushi , without eschar, is a febrile illness that mimics malaria (ML), dengue (DG), and other rickettsioses such as murine typhus (MT). Comparative analysis of microarray gene expression profiles of GSE16463 dataset, from O. tsutsugamushi infected monocytes, was performed to identify transcriptional signatures in ST discriminated from other acute febrile infections, accompanied by functional pathways and enrichment analysis in disease pathogenesis. A unique 31 ST-associated signature genes obtained in this study could help distinguish ST from other febrile illnesses DG, ML and MT. The functional pathways significantly enriched in ST disease group included translocation of ZAP-70 to immunological synapse, and phosphorylation of CD3 and TCR zeta chains, involving PTPN22 and CD3G genes, which could further help in the understanding of molecular pathophysiology of ST and discovering novel drug targets as well as vaccine developments." @default.
- W3114752783 created "2021-01-05" @default.
- W3114752783 creator A5004450317 @default.
- W3114752783 creator A5075559072 @default.
- W3114752783 date "2020-12-23" @default.
- W3114752783 modified "2023-09-27" @default.
- W3114752783 title "Differential gene expression in scrub typhus compared to other acute febrile infections by bioinformatic approaches" @default.
- W3114752783 cites W1571861186 @default.
- W3114752783 cites W1924891226 @default.
- W3114752783 cites W1973094248 @default.
- W3114752783 cites W1996158844 @default.
- W3114752783 cites W2004555770 @default.
- W3114752783 cites W2027211850 @default.
- W3114752783 cites W2103912979 @default.
- W3114752783 cites W2109788141 @default.
- W3114752783 cites W2118258530 @default.
- W3114752783 cites W2158408029 @default.
- W3114752783 cites W2159675211 @default.
- W3114752783 cites W2163899891 @default.
- W3114752783 cites W2804734165 @default.
- W3114752783 cites W2950764390 @default.
- W3114752783 cites W3040484144 @default.
- W3114752783 cites W3092372833 @default.
- W3114752783 doi "https://doi.org/10.1101/2020.12.21.20248609" @default.
- W3114752783 hasPublicationYear "2020" @default.
- W3114752783 type Work @default.
- W3114752783 sameAs 3114752783 @default.
- W3114752783 citedByCount "0" @default.
- W3114752783 crossrefType "posted-content" @default.
- W3114752783 hasAuthorship W3114752783A5004450317 @default.
- W3114752783 hasAuthorship W3114752783A5075559072 @default.
- W3114752783 hasBestOaLocation W31147527831 @default.
- W3114752783 hasConcept C104317684 @default.
- W3114752783 hasConcept C142724271 @default.
- W3114752783 hasConcept C150194340 @default.
- W3114752783 hasConcept C159047783 @default.
- W3114752783 hasConcept C203014093 @default.
- W3114752783 hasConcept C2777747896 @default.
- W3114752783 hasConcept C2778861743 @default.
- W3114752783 hasConcept C2779528086 @default.
- W3114752783 hasConcept C2780206043 @default.
- W3114752783 hasConcept C2780823208 @default.
- W3114752783 hasConcept C2780942790 @default.
- W3114752783 hasConcept C533803919 @default.
- W3114752783 hasConcept C54355233 @default.
- W3114752783 hasConcept C71924100 @default.
- W3114752783 hasConcept C86803240 @default.
- W3114752783 hasConceptScore W3114752783C104317684 @default.
- W3114752783 hasConceptScore W3114752783C142724271 @default.
- W3114752783 hasConceptScore W3114752783C150194340 @default.
- W3114752783 hasConceptScore W3114752783C159047783 @default.
- W3114752783 hasConceptScore W3114752783C203014093 @default.
- W3114752783 hasConceptScore W3114752783C2777747896 @default.
- W3114752783 hasConceptScore W3114752783C2778861743 @default.
- W3114752783 hasConceptScore W3114752783C2779528086 @default.
- W3114752783 hasConceptScore W3114752783C2780206043 @default.
- W3114752783 hasConceptScore W3114752783C2780823208 @default.
- W3114752783 hasConceptScore W3114752783C2780942790 @default.
- W3114752783 hasConceptScore W3114752783C533803919 @default.
- W3114752783 hasConceptScore W3114752783C54355233 @default.
- W3114752783 hasConceptScore W3114752783C71924100 @default.
- W3114752783 hasConceptScore W3114752783C86803240 @default.
- W3114752783 hasLocation W31147527831 @default.
- W3114752783 hasOpenAccess W3114752783 @default.
- W3114752783 hasPrimaryLocation W31147527831 @default.
- W3114752783 hasRelatedWork W1894988991 @default.
- W3114752783 hasRelatedWork W2019583992 @default.
- W3114752783 hasRelatedWork W2020415155 @default.
- W3114752783 hasRelatedWork W2061222893 @default.
- W3114752783 hasRelatedWork W2094172090 @default.
- W3114752783 hasRelatedWork W2107109582 @default.
- W3114752783 hasRelatedWork W2126728789 @default.
- W3114752783 hasRelatedWork W2489036187 @default.
- W3114752783 hasRelatedWork W2941121719 @default.
- W3114752783 hasRelatedWork W2187424221 @default.
- W3114752783 isParatext "false" @default.
- W3114752783 isRetracted "false" @default.
- W3114752783 magId "3114752783" @default.
- W3114752783 workType "article" @default.