Matches in SemOpenAlex for { <https://semopenalex.org/work/W3114816694> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3114816694 abstract "Abstract Background Periprocedural antithrombotic medication after mechanical thrombectomy (MT) for acute intracranial large vessel occlusion (LVO) is still controversial. Recent studies have indicated that majority of stroke with undetermined etiology (SUE), as defined by the TOAST classification, showed strong overlap with cardioembolic stroke (CE). We intended to determine the efficacy of the mono antiplatelet (MA) therapy in both stroke types after receiving successful MT recanalization in the acute stage. Methods 178 consecutive stroke patients who received MT treatment were retrospectively analyzed. CE and SUE type stroke patients were chosed to received MA therapy. Aspirin 100mg or clopidogrel 75 mg was added immediate for patients who didn`t received intravenously recombinant tissue plasminogen activator (IV-rtPA) and after 24 hours for those received IV-rtPA if symptomatic intracranial hemorrhage (sICH) was not found. MA treatment outcomes included recanalized artery patency, subsequent sICH and functional independence (mRS score of 0-2) were compared between two stroke types. Results Successful recanalization (TICI 2b/3) was achieved in 75 CE stroke patients and 50 SUE patients without hemorrhagic transformation were included into final analysis. Target artery at 7 days after recanalization was confirmed 100% patency in the CE group and 97.5% in the SUE group. Hemorrhagic transformation after 24h was found in 26% patients in the SUE group and in 26.7% patients in the CE group (P > 0.05). sICH was confirmed in 3 patients in the SUE group and in 10 patients in the CE group. At 90 days, 45.8% in the SUE group and 46.5% in the CE group of patients had achieved good outcomes (mRs 0-2) (P=1.00). However, accumulative death was higher in the CE group than in the SUE group (21% vs. 15%; P=0.47) Conclusion Mono antiplatelet strategy for the treatment of accurate stage of cardioembolic stroke received mechanical thrombectomy is safe and effective. Meanwhile, for patients considered SUE stroke type, mono antiplatelet therapy after thrombectomy achieved similar treatment outcomes as compared to cardioembolic stroke patients." @default.
- W3114816694 created "2021-01-05" @default.
- W3114816694 creator A5015798924 @default.
- W3114816694 creator A5016894561 @default.
- W3114816694 creator A5017376277 @default.
- W3114816694 creator A5032296049 @default.
- W3114816694 creator A5036860283 @default.
- W3114816694 creator A5059839384 @default.
- W3114816694 creator A5060232994 @default.
- W3114816694 creator A5060509734 @default.
- W3114816694 date "2020-02-11" @default.
- W3114816694 modified "2023-09-26" @default.
- W3114816694 title "Efficacy and Safety of Mono Antiplatelet Treatment for Cardioembolic and Undetermined Etiological Stroke after Receiving Successful Mechanical Thrombectomy" @default.
- W3114816694 doi "https://doi.org/10.21203/rs.2.23071/v1" @default.
- W3114816694 hasPublicationYear "2020" @default.
- W3114816694 type Work @default.
- W3114816694 sameAs 3114816694 @default.
- W3114816694 citedByCount "0" @default.
- W3114816694 crossrefType "posted-content" @default.
- W3114816694 hasAuthorship W3114816694A5015798924 @default.
- W3114816694 hasAuthorship W3114816694A5016894561 @default.
- W3114816694 hasAuthorship W3114816694A5017376277 @default.
- W3114816694 hasAuthorship W3114816694A5032296049 @default.
- W3114816694 hasAuthorship W3114816694A5036860283 @default.
- W3114816694 hasAuthorship W3114816694A5059839384 @default.
- W3114816694 hasAuthorship W3114816694A5060232994 @default.
- W3114816694 hasAuthorship W3114816694A5060509734 @default.
- W3114816694 hasBestOaLocation W31148166941 @default.
- W3114816694 hasConcept C126322002 @default.
- W3114816694 hasConcept C127413603 @default.
- W3114816694 hasConcept C137627325 @default.
- W3114816694 hasConcept C141071460 @default.
- W3114816694 hasConcept C2777015399 @default.
- W3114816694 hasConcept C2777628954 @default.
- W3114816694 hasConcept C2777849778 @default.
- W3114816694 hasConcept C2779581417 @default.
- W3114816694 hasConcept C2780645631 @default.
- W3114816694 hasConcept C2780931571 @default.
- W3114816694 hasConcept C2911092318 @default.
- W3114816694 hasConcept C3020199598 @default.
- W3114816694 hasConcept C500558357 @default.
- W3114816694 hasConcept C541997718 @default.
- W3114816694 hasConcept C71924100 @default.
- W3114816694 hasConcept C78519656 @default.
- W3114816694 hasConceptScore W3114816694C126322002 @default.
- W3114816694 hasConceptScore W3114816694C127413603 @default.
- W3114816694 hasConceptScore W3114816694C137627325 @default.
- W3114816694 hasConceptScore W3114816694C141071460 @default.
- W3114816694 hasConceptScore W3114816694C2777015399 @default.
- W3114816694 hasConceptScore W3114816694C2777628954 @default.
- W3114816694 hasConceptScore W3114816694C2777849778 @default.
- W3114816694 hasConceptScore W3114816694C2779581417 @default.
- W3114816694 hasConceptScore W3114816694C2780645631 @default.
- W3114816694 hasConceptScore W3114816694C2780931571 @default.
- W3114816694 hasConceptScore W3114816694C2911092318 @default.
- W3114816694 hasConceptScore W3114816694C3020199598 @default.
- W3114816694 hasConceptScore W3114816694C500558357 @default.
- W3114816694 hasConceptScore W3114816694C541997718 @default.
- W3114816694 hasConceptScore W3114816694C71924100 @default.
- W3114816694 hasConceptScore W3114816694C78519656 @default.
- W3114816694 hasLocation W31148166941 @default.
- W3114816694 hasOpenAccess W3114816694 @default.
- W3114816694 hasPrimaryLocation W31148166941 @default.
- W3114816694 hasRelatedWork W1508862217 @default.
- W3114816694 hasRelatedWork W1584895772 @default.
- W3114816694 hasRelatedWork W1974609923 @default.
- W3114816694 hasRelatedWork W2031270414 @default.
- W3114816694 hasRelatedWork W2033838449 @default.
- W3114816694 hasRelatedWork W2347977317 @default.
- W3114816694 hasRelatedWork W2386750629 @default.
- W3114816694 hasRelatedWork W2753217352 @default.
- W3114816694 hasRelatedWork W2926542596 @default.
- W3114816694 hasRelatedWork W95487621 @default.
- W3114816694 isParatext "false" @default.
- W3114816694 isRetracted "false" @default.
- W3114816694 magId "3114816694" @default.
- W3114816694 workType "article" @default.