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- W3114839110 abstract "In the last decades, DNA has been considered far more than the system carrying the essential genetic instructions. Indeed, because of the remarkable properties of the base-pairing specificity and thermoreversibility of the interactions, DNA plays a central role in the design of innovative architectures at the nanoscale. Here, combining complementary DNA strands with a custom-made solution of silver nanoparticles, we realize plasmonic aggregates to exploit the sensitivity of Surface Enhanced Raman Spectroscopy (SERS) for the identification/detection of the distinctive features of DNA hybridization, both in solution and on dried samples. Moreover, SERS allows monitoring the DNA aggregation process by following the temperature variation of a specific spectroscopic marker associated with the Watson-Crick hydrogen bond formation. This temperature-dependent behavior enables us to precisely reconstruct the melting profile of the selected DNA sequences by spectroscopic measurements only." @default.
- W3114839110 created "2021-01-05" @default.
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- W3114839110 date "2021-02-01" @default.
- W3114839110 modified "2023-09-23" @default.
- W3114839110 title "Exploiting SERS sensitivity to monitor DNA aggregation properties" @default.
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- W3114839110 doi "https://doi.org/10.1016/j.ijbiomac.2020.12.039" @default.
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