FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3115294950> ?p ?o ?g. }

• W3115294950 endingPage "276" @default.
• W3115294950 startingPage "264" @default.
• W3115294950 abstract "Background: Gastroesophageal reflux disease is associated with Barrett esophagus, esophageal adenocarcinoma, and significantly impacts quality of life. Medical management is the first line therapy with surgical fundoplication as an alternative therapy. However, a small portion of patients who fail medical therapy are referred for surgical consultation. This creates a “gap” in therapy for those patients dissatisfied with medical therapy but are not getting referred for surgical consultation. Three procedures have been designed to address these patients. These include radiofrequency ablation (RFA) of the lower esophageal sphincter, transoral incisionless fundoplication (TIF), and magnetic sphincter augmentation. Materials and Methods: A Pubmed literature review was conducted of all publications for RFA, TIF, and MSA. Four most common endpoints for the 3 procedures were compared at different intervals of follow-up. These include percent of patients off proton pump inhibitors (PPIs), GERD-HRQL score, DeMeester score, and percent of time with pH <4. A second query was performed for patients treated with PPI and fundoplications to match the same 4 endpoints as a control. Results: Variable freedom from PPI was reported at 1 year for RFA with a weighted mean of 62%, TIF with a weighted mean of 61%, MSA with a weighted mean of 85%, and fundoplications with a weighted mean of 84%. All procedures including PPIs improved quality-of-life scores but were not equal. Fundoplication had the best improvement followed by MSA, TIF, RFA, and PPI, respectively. DeMeester scores are variable after all procedures and PPIs. All MSA studies showed normalization of pH, whereas only 4 of 17 RFA studies and 3 of 11 TIF studies reported normalization of pH. Conclusions: Our literature review compares 3 rival procedures to treat “gap” patients for gastroesophageal reflux disease with 4 common endpoints. Magnetic sphincter augmentation appears to have the most reproducible and linear outcomes but is the most invasive of the 3 procedures. MSA outcomes most closely mirrors that of fundoplication." @default.
• W3115294950 created "2021-01-05" @default.
• W3115294950 creator A5042624237 @default.
• W3115294950 creator A5044782438 @default.
• W3115294950 creator A5059989236 @default.
• W3115294950 creator A5070957071 @default.
• W3115294950 creator A5072545032 @default.
• W3115294950 date "2020-12-16" @default.
• W3115294950 modified "2023-10-02" @default.
• W3115294950 title "Mind the Gap: Current Treatment Alternatives for GERD Patients Failing Medical Treatment and Not Ready for a Fundoplication" @default.
• W3115294950 cites W1420612598 @default.
• W3115294950 cites W1521643570 @default.
• W3115294950 cites W164136523 @default.
• W3115294950 cites W1841919849 @default.
• W3115294950 cites W1965863562 @default.
• W3115294950 cites W1969992846 @default.
• W3115294950 cites W1970237082 @default.
• W3115294950 cites W1971557122 @default.
• W3115294950 cites W1971586050 @default.
• W3115294950 cites W1972580224 @default.
• W3115294950 cites W1972683670 @default.
• W3115294950 cites W1972912781 @default.
• W3115294950 cites W1973206156 @default.
• W3115294950 cites W1973416857 @default.
• W3115294950 cites W1973616778 @default.
• W3115294950 cites W1975802418 @default.
• W3115294950 cites W1977905768 @default.
• W3115294950 cites W1981091296 @default.
• W3115294950 cites W1982528814 @default.
• W3115294950 cites W1987363278 @default.
• W3115294950 cites W1987965528 @default.
• W3115294950 cites W1988220078 @default.
• W3115294950 cites W1989430071 @default.
• W3115294950 cites W1993775264 @default.
• W3115294950 cites W1995246404 @default.
• W3115294950 cites W1998801726 @default.
• W3115294950 cites W2004830815 @default.
• W3115294950 cites W2005004702 @default.
• W3115294950 cites W2007155226 @default.
• W3115294950 cites W2009002435 @default.
• W3115294950 cites W2009122048 @default.
• W3115294950 cites W2011817209 @default.
• W3115294950 cites W2014591992 @default.
• W3115294950 cites W2016049902 @default.
• W3115294950 cites W2016111768 @default.
• W3115294950 cites W2018230193 @default.
• W3115294950 cites W2018785013 @default.
• W3115294950 cites W2020658227 @default.
• W3115294950 cites W2021776211 @default.
• W3115294950 cites W2022113744 @default.
• W3115294950 cites W2024140807 @default.
• W3115294950 cites W2025192628 @default.
• W3115294950 cites W2025434100 @default.
• W3115294950 cites W2025755585 @default.
• W3115294950 cites W2027356876 @default.
• W3115294950 cites W2028357417 @default.
• W3115294950 cites W2029663316 @default.
• W3115294950 cites W2031875441 @default.
• W3115294950 cites W2035945738 @default.
• W3115294950 cites W2038215468 @default.
• W3115294950 cites W2038263657 @default.
• W3115294950 cites W2040998154 @default.
• W3115294950 cites W2042015969 @default.
• W3115294950 cites W2043640958 @default.
• W3115294950 cites W2048885015 @default.
• W3115294950 cites W2050464941 @default.
• W3115294950 cites W2052271808 @default.
• W3115294950 cites W2053011521 @default.
• W3115294950 cites W2054004882 @default.
• W3115294950 cites W2054362293 @default.
• W3115294950 cites W2060042222 @default.
• W3115294950 cites W2061269310 @default.
• W3115294950 cites W2062717770 @default.
• W3115294950 cites W2071521423 @default.
• W3115294950 cites W2073202497 @default.
• W3115294950 cites W2073362875 @default.
• W3115294950 cites W2073913054 @default.
• W3115294950 cites W2078005623 @default.
• W3115294950 cites W2082253687 @default.
• W3115294950 cites W2089668833 @default.
• W3115294950 cites W2091471784 @default.
• W3115294950 cites W2091736559 @default.
• W3115294950 cites W2092105059 @default.
• W3115294950 cites W2095347844 @default.
• W3115294950 cites W2096673219 @default.
• W3115294950 cites W2100630348 @default.
• W3115294950 cites W2104434915 @default.
• W3115294950 cites W2110114397 @default.
• W3115294950 cites W2111368978 @default.
• W3115294950 cites W2116833393 @default.
• W3115294950 cites W2118912135 @default.
• W3115294950 cites W2121162625 @default.
• W3115294950 cites W2121757814 @default.
• W3115294950 cites W2122946867 @default.
• W3115294950 cites W2126705466 @default.
• W3115294950 cites W2128012169 @default.
• W3115294950 cites W2132251388 @default.
• W3115294950 cites W2140687039 @default.

• next